1. Rejuvenation Research Journal - life span can be extended in old mice by transplant of a young thymus.
The Thymus is source of T-cells, which are your active immune system.
Rejuvenating your immune system would improve health and lifespan.
2. Fighting Aging.org - Rapamycin, an immunosuppressant which extends the life of older mice to a signicant level effects long term memory formation
3. Fighting Aging.org -mitochondrial uncoupling research shows promise for increasing health and lifespan
Repair of damaged mitochondria throughout the body should have a far greater effect on longevity than any change to metabolism that merely slows the accumulation of damage - and such repair technologies are comparatively close to fruition.
4. Fightaging.org looks at progess in stem cell science
Progress is being made to the goal of low-cost and reliable sources of specific cell populations, and ways to quickly generate those sources from a patient's own cells.