Coverage of Disruptive Science and Technology
January 28, 2013
Calorie Restricted Telomerase Enhanced Mice Live Longer and Healthier
Fightaging reports that researchers have tried out calorie restriction (CR) on their transgenic telomerase-enhanced (TgTERT) mice,
with a wild-type (WT) control group. Apparently calorie restriction somewhat synergizes with the effects of additional telomerase, and thus calorie restricted TgTERT mice live longer than their ad libitum peers. Beyond that, this is also a study of how calorie restriction impacts telomere dynamics, finding that it delays the characteristic erosion of telomeres with age - which is consistent with the body of research showing calorie restriction to slow almost all other measurable aspects of aging.
PLOS One - Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity
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