They provide the following:
- BAM file (roughly 50 GB)
- variant summary reports from SnpEff and VEP
- autosomal and chrX variant identification (as two VCF files):
- novel variants (annotated with SnpEff and VEP)
- results for a set of over 100 million known SNPs from dbSNP build 142
- mtDNA sequence (as FASTA file)
- Y-DNA analysis (for males)
Powering Population-Scale Human Whole-Genome Sequencing (WGS)
The HiSeq X Ten System is the most powerful sequencing platform ever created. The system consists of a set of 10 HiSeq X ultra-high-throughput instruments that deliver over 18,000 human genomes per year at the price of $1000 per genome. The HiSeq X Ten makes human whole-genome sequencing more affordable and accessible than ever before.
World’s First $1000 Human Genome
This sequencing solution is the world’s first to break the thousand dollar human genome barrier. Each HiSeq X System can sequence a human genome at 30x coverage or greater for significantly less than $1000 in consumables. When used at scale, the HiSeq X Ten delivers a $1000 genome, inclusive of instrument depreciation, DNA extraction, library preparation, and estimated labor for a typical high-throughput genomics laboratory.
Non-Human Species Expansion
HiSeq X Sequencing System customers can now apply population-scale sequencing to non-human species. The HiSeq X System delivers high coverage in a variety of areas, including agriculture and model organism research in the pharmaceutical industry. By providing ultrahigh throughput and an unprecedented price point per genome, the HiSeq X System now provides customers with an opportunity to reshape the economics and scale of whole-genome sequencing beyond the human species.