Two longevity (antiaging) nonprofits – SENS Research Foundation and Lifespan.io (Lifespan Extension Advocacy Foundation) – have unveiled plans to merge, upon completion of regulatory approvals. Founded in 2009, SENS Research Foundation, has funded cutting-edge research into the science of aging and regenerative medicine. Lifespan.io is a dynamic hub for advancing the frontier of longevity research. …
The all-treatments group is still taking roughly twice as long as the all-controls group (starting from 19 months old, when the experiment began) to get down to a given survival percentage in males. The all treatments female mice are lasting 50% longer than controls. It’ll still be a few months before we can start to …
The mole rat lives about 37 years which is about five times longer than expected for an animal of its size and type. Researchers at the Queen Mary University of London have learned more about why the mole rat lives so long. The mole rat have fewer heart attacks. The mole rat adaptions to low …
Low-protein diets promote health and longevity in diverse species. Restriction of the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine recapitulates many of these benefits in young C57BL/6J mice. Restriction of dietary isoleucine (IleR) is sufficient to promote metabolic health and is required for many benefits of a low-protein diet in C57BL/6J males. Here, we …
There is a large scale study using 1000 mice testing four major life extension therapies to see if there is an additive effect and how much additive effect there is. Preliminary data is show there can be longer lifespans with combined therapies. There have been different life extension therapies where each on there own can …
Brian Wang and Randy Kirk discussed the expected biggest science and technology stories of 2024. The potentially biggest development in 2024 could be antiaging science reaching a milestone of doubling the remaining lifespan of a mouse. The Longevity Escape velocity program has take four promising anti-aging treatments and applied them in various combinations to a …
Researchers have now taken a step toward that vision of molecular systems that repair cells inside the human body. Molecular repair built from a patient’s own cells will eventually ferret out cancer, repair injured tissue, and even remove plaque from blood vessels. They have gotten tracheal cells to form coordinated groups called organoids that can …
Approaches to achieving radical life extension involve many scientific unknowns. There is uncertainty around whether the different forms of aging damage can be repaired. There is an approach to immortality that replaces scientific unknowns with huge technical challenges. The technically challenging approach is: 1. Rejuvenate the body by growing a body using an egg cell …
The Ship of Theseus is a thought experiment about whether an object which has had all of its original components replaced remains the same object. Theseus, the mythical Greek founder-king of Athens, rescued the children of Athens from King Minos after slaying the minotaur and then escaped onto a ship going to Delos. Each year, …
Brain plasticity is key to making progressive brain tissue replacement work. Various brain functions can move to different parts of the brain. Jean Hebert plan would be to grow a new body with gene therapy to knockout brain development. The body would need to be kept on life support for 14-18 years until the skull …
