David Chalmers will be there talking about uploading. The Summit is branching out into topics like biotechnology and decision theory instead of just robotics and AI. Peter Thiel, who backed SENS (Strategies for Engineered Negligible Senescence) with $3.5 million in funding, will be speaking as well.
Ned Seeman [Prolific DNA Nanotechnology pioneer], Robin Hanson and many others will be speaking.
Here are highlights of the 2008 Singularity Summit.
Kurzweil AI has some information as well.

Brian Wang is a Futurist Thought Leader and a popular Science blogger with 1 million readers per month. His blog Nextbigfuture.com is ranked #1 Science News Blog. It covers many disruptive technology and trends including Space, Robotics, Artificial Intelligence, Medicine, Anti-aging Biotechnology, and Nanotechnology.
Known for identifying cutting edge technologies, he is currently a Co-Founder of a startup and fundraiser for high potential early-stage companies. He is the Head of Research for Allocations for deep technology investments and an Angel Investor at Space Angels.
A frequent speaker at corporations, he has been a TEDx speaker, a Singularity University speaker and guest at numerous interviews for radio and podcasts. He is open to public speaking and advising engagements.