Stem cell treatment of Parkinson’s disease via half inch holes in the skull

Kyoto University Hospital will start clinical trials for Parkinson’s disease that transplants dopaminergic progenitors generated from induced pluripotent stem (iPS) cells.

About 5 million iPS cell-derived dopaminergic progenitors will be transplanted by stereotaxic brain surgery into the left and right sides of the patient’s putamen.

A 12mm diameter hole will be drilled on the patient’s skull, and stem cells will be injected using a specialized device.

Patient aged between 50 and 69 will participate in the trial and their progress will be monitored for two years.

About 10 million people in the world have Parkinson’s. About one million people in the USA have Parkinson’s.

16 thoughts on “Stem cell treatment of Parkinson’s disease via half inch holes in the skull”

  1. I was diagnosed with Parkinson’s disease 3 years ago at the age of 59. For several months I had noticed tremors in my right hand and the shaking of my right foot when I was sitting. My normally beautiful cursive writing was now small cramped printing. And I tended to lose my balance. Neurologist had me walk down the hall and said I didn’t swing my right arm. I had never noticed! I was in denial for a while as there is no history in my family of parents and five older siblings, but now accept I have classic symptoms. I am taking totalcureherbsfoundation.com herbal treatment  and am about to start physical therapy to strengthen muscles.this herbal treatment has full get rid of my PD after 15 weeks of usage and it has reversed all symptoms.

  2. What would be nice is if the statistics were included that led to this human trial. Was there a success rate? Is this a breakthrough or just a marginally successful procedure?

  3. What would be nice is if the statistics were included that led to this human trial. Was there a success rate? Is this a breakthrough or just a marginally successful procedure?

  4. These aren’t adult stem cells, these are derived from iPSCs which are reprogrammed somatic cells. I don’t think you can say adult stem cells are more useful than embryonic, I’d argue the opposite is true, however you are correct that embryonic stem cells can be ethically contentious. That’s one of the major positives of iPSCs.

  5. These aren’t adult stem cells these are derived from iPSCs which are reprogrammed somatic cells. I don’t think you can say adult stem cells are more useful than embryonic I’d argue the opposite is true however you are correct that embryonic stem cells can be ethically contentious. That’s one of the major positives of iPSCs.

  6. These aren’t adult stem cells, these are derived from iPSCs which are reprogrammed somatic cells. I don’t think you can say adult stem cells are more useful than embryonic, I’d argue the opposite is true, however you are correct that embryonic stem cells can be ethically contentious. That’s one of the major positives of iPSCs.

  7. What would be nice is if the statistics were included that led to this human trial. Was there a success rate? Is this a breakthrough or just a marginally successful procedure?

  8. One useful rule of thumb is that the things that you eat that help your skin, often help your brain as well, because they derive from the same tissue during development (the ectoderm).

  9. Turmeric there’s good science on, but I have to echo Doc’s question re the maple syrup and raw honey.

    And no matter how careful we are, or what things we imbibe, promises that we won’t suffer from “any” old age brain disease seem to stretch what is actually possible right now.

  10. Once again, adult stem cells prove more useful than the ethically dubious embryonic type.

    Re Kimhi’s post, Turmeric has been shown to be helpful for the brain, and I suspect adequate vitamin D is as well. So have chocolate, fish, olive oil, and coffee. Likely the one thing these have in common is anti-inflammatory effects, as inflammation seems to be key to many ills.

  11. Make a tea a tablespoon of turmeric and dark organic maple syrup or raw honey and go out to the sun during low radiation hours for 30 min and you are not going to suffer from any old age brain disease.

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