James Tour says that Roswell is bringing to world the $100 genome that can scale rapidly and also deliver Exabyte data storage.
Paul Mola is the Founder, and CEO of Roswell Biotechnologies. Roswell could enable DNA storage technology. This would have exabyte capabilties. They have millions to billions of DNA readers on CMOS ships. They can read DNA, proteins, and other biomolecules with the speed and economics required for a complete and useful data storage and retrieval system.
DNA can hold ten terabytes of data and can perform trillions of parallel calculations.
Roswell is creating molecular electronic sensors on CMOS chips. (this is discussed at 10 minutes in the video). They are trying to create enough pixels to read a whole genome. They are working on the sequencing chemistry and enzymes for this system. They integrate the chemistry via an electronic signal that is then read by electronics. They plan to be commercialized in one to two years.
They want to use different molecules for different processes.
They could eventually use molecules to scale beyond CMOS.
In 2017, George Church’s group at Harvard adopted CRISPR DNA-editing technology to record images of a human hand into the genome of E. coli, which were read out with higher than 90 percent accuracy.
In 2018, the University of Washington, Microsoft, and Twist Bioscience published work where they encoded 200 Mb of information in DNA, and retrieved this data with 100% accuracy, which is believed to be the largest DNA-based storage project to date.
Microsoft and Twist Bioscience are working on DNA-storage technology.
In June 2019, scientists reported that all 16 GB of Wikipedia have been encoded into synthetic DNA. Startup Catalog placed all of the text of Wikipedia’s English-language version onto the same genetic molecules our own bodies use. Catalog’s DNA writing machine can write data at a rate of 4 megabits per second, but the company hopes to make it at least a thousand times faster.
Silicon-powered DNA Synthesis
Twist Bioscience developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a high-throughput silicon platform that allows us to miniaturize the chemistry necessary for DNA synthesis. This miniaturization allows us to reduce the reaction volumes by a factor of 1,000,000 while increasing throughput by a factor of 1,000, enabling the synthesis of 9,600 genes on a single silicon chip at full scale.
* DNA is nature’s permanent data storage
* Dense and compact enough to fit the entire internet in a shoebox
* Extreme low energy storage that uses less than a light bulb’s worth of power per year
* Universal read technology that will last hundreds of years
* Simple to make redundant storage
* Encrypt and conceal important data