Reading and Writing DNA has improved 2 to 10 times faster than Moore’s Law over the last 35 years. There has been over 10 million times improvement.
Molecular and cell multiplexing enable atomically precise reactions at 1 trillion reactions per droplet.
George Church giving a similar talk with overlap in the slides.
Germline vs Somatic Gene Therapy
1. Billion-fold lower off-target (due to cell #)
2. Clonality allows checking (additional million-fold)
3. Immune Tolerance
4. 100% Delivery to every cell
5. $0 to subsequent generations
1. Very long term clinical trials >20 years
2. 130 newborns/yr vs 7.7 billion total
The Genome in a Bottle Consortium is a public-private-academic consortium hosted by NIST to develop the technical infrastructure (reference standards, reference methods, and reference data) to enable translation of whole human genome sequencing to clinical practice.
Brian Wang is a Futurist Thought Leader and a popular Science blogger with 1 million readers per month. His blog Nextbigfuture.com is ranked #1 Science News Blog. It covers many disruptive technology and trends including Space, Robotics, Artificial Intelligence, Medicine, Anti-aging Biotechnology, and Nanotechnology.
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