Moderna COVID Vaccine is 94.5% Effective

Moderna, Inc. (Nasdaq: MRNA) reported the results of its Phase 3 study of mRNA-1273 has met the statistical criteria pre-specified in the study protocol for efficacy, with a vaccine efficacy of 94.5%.

A secondary endpoint analyzed severe cases of COVID-19 and included 11 severe cases (as defined in the study protocol) in this first interim analysis. All 11 cases occurred in the placebo group and none in the mRNA-1273 vaccinated group.

The 95 COVID-19 cases included 15 older adults (ages 65+) and 20 participants identifying as being from diverse communities (including 12 Hispanic or LatinX, 4 Black or African Americans, 3 Asian Americans and 1 multiracial).

The interim analysis included a concurrent review of the available Phase 3 COVE study safety data by the DSMB, which did not report any significant safety concerns. A review of solicited adverse events indicated that the vaccine was generally well tolerated. The majority of adverse events were mild or moderate in severity. Grade 3 (severe) events greater than or equal to 2% in frequency after the first dose included injection site pain (2.7%), and after the second dose included fatigue (9.7%), myalgia (8.9%), arthralgia (5.2%), headache (4.5%), pain (4.1%) and erythema/redness at the injection site (2.0%). These solicited adverse events were generally short-lived. These data are subject to change based on ongoing analysis of further Phase 3 COVE study data and final analysis.

Preliminary analysis suggests a broadly consistent safety and efficacy profile across all evaluated subgroups.

Moderna intends to submit for an Emergency Use Authorization (EUA) with the U.S. Food and Drug Administration (FDA) in the coming weeks and anticipates having the EUA informed by the final safety and efficacy data (with a median duration of at least 2 months). Moderna also plans to submit applications for authorizations to global regulatory agencies.

Moderna is working with the U.S. Centers for Disease Control and Prevention (CDC), Operation Warp Speed and McKesson (NYSE: MCK), a COVID-19 vaccine distributor contracted by the U.S. government, as well as global stakeholders to be prepared for distribution of mRNA-1273, in the event that it receives an EUA and similar global authorizations. By the end of 2020, the Company expects to have approximately 20 million doses of mRNA-1273 ready to ship in the U.S. The Company remains on track to manufacture 500 million to 1 billion doses globally in 2021.

SOURCES- Moderna
Written By Brian Wang,

35 thoughts on “Moderna COVID Vaccine is 94.5% Effective”

  1. For a start, the idea that adding more oxygen causes hypoxia is expanded out into a far more complex, and non-self-contradictory, multistage process.

    For those wanting to play along at home, the subjects breathed pure oxygen at 2 atmospheres for 90 minutes per day for 60 days. Not something that can be done on the cheap, but also something that believably could produce significant physiological changes.

    And the sheer expense of such a treatment means only 30 subjects, so this isn't a great data set. But a 30% increase in telomere length AND decrease in senescent cells is a really material effect size.

    Caution: Pure oxygen at 2 atmospheres is NOT SAFE. You can do things like set your clothes on fire through static electric sparks.

  2. Now THAT's a source I can take seriously. Even gives open source links to the original paper.

    Bravo good Sir! (Or Ma'am as the case may be.)

  3. Getting news from Yahoo now? I'll wait till it's on a more reputable site like tumblr or 4chan.

    More seriously: If you do a search on this "breakthrough", you find it reported all over the world, but not in any actual science journals that I could find. It was all things like yahoo, and popular mechanics and and

    Very suspicious.

    Furthermore, it has lines like "The pressurised chamber allows more oxygen to be dissolved into the tissues and mimics a state of "hypoxia", or oxygen shortage, which is known to have regenerating effects." which indicates that what we are reading has gone through several layers of people who don't know what the words they are writing actually mean. So who knows what the original scientists were actually saying?

  4. Wait until folks realize toasters in water could've halted this entire thing before it ever started! They're gonna be LIT! xD

    "You mean I could have just dropped my EasyBake into my bubble bath and NOT gone to the hospital? Mother[BEEP]kin figures!!!

  5. Are you talking about the moron who said in March that the president couldn't shutdown his state, or the moron who put a bunch of COVID positive people into nursing homes?

  6. A Phase 3 clinical trial is designed, by medical statisticians, to provide exactly that sort of information.

    Now they don't always get it right, and that's why they have Phase 4. That's where they catch all the weird edge cases like interactions with rare conditions etc.

    But the question has already been looked at, not ignored.

  7. Read your own post again. It is not a good trait not having a self correcting mechanism for your beliefs. Ask a parent or trusted adult for assistance in validating posts you find on online blog sites.

  8. And at the beginning, they told us not to wear masks, for a variety of valid reasons. Mistakes were made, including the daily miscues from the moron in office.

  9. It's statistics. The larger and more randomized is the population of a study, the smaller is the error margin

  10. There are almost 200 vaccines being developed in China, here is one of the two I was talkling about. This is from a couple of month ago.
    Another candidate vaccine, called CoronaVac , being developed by Beijing-based Sinovac Biotech, protected rhesus macaque monkeys from infection with the novel coronavirus, according to a study published July 3 in the journal Science. The company, having already shown the vaccine to be safe and effective in early clinical trials, is recruiting for a phase 3 clinical trial with 8,870 participants in Brazil, according to
    This vaccine is made up of an inactivated version of the SARS-CoV-2 virus. Inactivated vaccines are the dead version of the pathogen that causes the disease (as opposed to weakened viruses which are live vaccines), according to the U.S. Department of Health and Human Services (HHS). Inactivated viruses such as the flu vaccine or the hepatitis A vaccine, are typically not as protective as live vaccines and might require booster shots over time, according to the HHS. In contrast, the Oxford vaccine is a weakened form of a live vaccine, which can create long-lasting immune responses but tends to be riskier for people with weakened immune systems or other health problems, according to the HHS.

  11. The Chinese one uses Adenovirus 5. I have been telling people for years Adenovirus 5, 36, & 37 are very dangerous. They likely caused the obesity epidemic and who knows what else. They have been soundly shown to cause obesity in animals. Ethically we can't do that test in humans for obvious reasons. The only other way to prove it is to vaccinate against it or cure it. But who would invest the money to do these things if it has not been proven to cause obesity? So Catch 22.
    I suppose if all the Chinese suddenly get fat, that would go a long way.
    The dang Russian one, Sputnik 2, is also based on Adenovirus 5. That may get the name Spud 2 if it turns you into a potato.

    And there is a reason the Chinese are ahead. They delayed giving the World the genome.

  12. "Cuomo bad mouthed a vaccine"

    You said same thing on the Pfizer post and u even provided a link to a twitter post. The transcript of your own link showed you were lying, here you are a week later doing the same thing when several pointed it out to u last week.

    Is it you have trouble reading/understanding your own news stories or you just want to believe something so badly you just ignore the details. Lots of people thumbs up your original lie as well as this one, is that why ?

    Transcript from own your link

    "Well, it’s good news/bad news. The good news is the Pfizer tests look good and we’ll have a vaccine shortly. The bad news is that it’s about two months before Joe Biden takes over and that means this administration is going to be implementing a vaccine plan. The vaccine plan is very important and it’s probably the most ambitious undertaking since Covid began. Just to put it in focus, we did 10 million Covid tests in this nation over seven months scrambling doing everything we can. We now have to do 330 million vaccinations, maybe twice, my state does more testing than any state in the United States. We did 12 million tests. We have to do 20 million vaccines. And the Trump Administration is rolling out the vaccination plan and I believe it’s flawed. I believe it learns nothing from the past. They’re basically going to have the private providers do it and that’s going to leave out all sorts of communities that were left out the first time when Covid ravaged them."

  13. Yes, but from the statistics of the vaccine tests and the laws of big numbers, there's already a pretty high degree of confidence about the final population numbers.

    It would be an incredible fluke if they chose a population that had a significantly different behavior than the rest of the population.

  14. More hilarious is that there are people who seem to think that Trump is spending time in the Pfizer labs and mucking with their beakers, bunsen burners and pipettes.

  15. The best will be a Chinese vaccine, That's what reports from Brazil, where many of these vaccines are being tested, say. They have a couple promising, one made from dead and another from weakened viruses. This way the body learns to recognize the whole range of signals from the virus. China, as usual coldly calculating its win win game, not only developed the virus, but also had a leg ahead in developing the antidotes to it.

  16. My question is, though, do we know it's actually that effective until it's been given to a large cross section of the population?

  17. In all honestly, even considering withholding a vaccine for something like this should really juat send someone straight to the gallows. Just teleport them. Not necessarily hanging, but, "Oh my God, all I did was THINK about withholding medical treatment for a severe illness from a few million people, and I have randomly ended up in a spot where people used to be hung. And it's, like, one of those really old places, too. The kind where they used to hang women who were falsely accused of witchcraft. I should probably not have those thoughts anymore."

    On the other hand, don't say something isn't effective if you KNOW that it's ineffective. That's kinda one of those things that you should be able to back up when you say it. That's how you get idiots to say, "Fine, if it's ineffective, I guess your people don't want it."

    It comes down to: Don't say dumb [CENSORED] and people won't say dumb [CENSORED] back to you.

    Nobody should feel they have to threaten to sue for a vaccine, though. It's not like anyone actually could withhold a vaccine for this virus once it's being distributed. Could try it, though. If they wanted to make things more interesting. What a fun day! ^_^!!!

  18. It's hilarious how Andrew Cuomo bad mouthed a vaccine just a month ago, and refused to allow it to be released in New York. Now he's whining that he'll sue if New York doesn't get the vaccine.

Comments are closed.