Demographics and the Transition to Over 200 Year Lifespans

The UN population projections assume that world lifespans increase from 72.6 today to 77 in 2050 and then about 82 in 2100. There are already populations that have life expectancy over 92 years. Asian American women in New Jersey life the longest. Decent genetics, near-optimal lifestyle and good healthcare can enable a life expectancy of …

Read more

THIO is a Telomerase-Mediated Approach to Fighting Cancer

Telomerase is present in 90% of human cancer cells and contributes significantly to proliferative abilities and immortality of cancer cells. MAIA Biotechnology is developing a Telomerase-Mediated Approach to Fighting Cancer. Telomerase is either absent or shows low activity in normal cells. THIO(6-thio-dG) is recognized by telomerase and incorporated into telomeres. Once incorporated, it compromises telomere …

Read more

George Church and Rejuvenate Bio’s Combination Gene Therapy Paper

Nextbigfuture has been eagerly awaiting the publication of the research paper on the scientific results of the combination gene therapy experiments by George Church and the team at Rejuvenate Bio. There was a video over one year ago where George Church mentioned being able to double the lifespan of mice. This would be three times …

Read more

Aubrey Updates on Antiaging Progress and Timing

In his talk at Ending Age-Related Diseases 2019, Estimating the True Complexity of Comprehensive Rejuvenation, SENS founder Aubrey de Grey talks about the intricacies of creating a complete rejuvenation biotechnology framework, including the differing rates of age-related damage and the ramifications of the extensive crosstalk between different types of this damage. The reason for grouping …

Read more

Longevity Biotech Startup Success and What Antiaging Success Might Look Like

In June 2019 at the Ending Age-Related Diseases 2019, James Peyer of Kronos BioVentures gave a talk about the investment aspects of rejuvenation biotechnology. He explained the effects of the population pyramid, showing the audience why cures for age-related diseases are such a necessity, and comparing population projections. One hundred years ago, the three leading …

Read more

Soft Cap Emitting Electromagnetic Waves has Reversed Memory Loss in Alzheimer’s patients

A bioengineered soft cap emitting electromagnetic waves has reversed memory impairment of Alzheimer’s patients (AD). This is a patient wearing MemorEM. CREDIT NeuroEM Therapeutics, Inc. Alzheimer’s Disease (AD) is disease of brain aging that causes progressive, severe memory loss. There is no effective “drug” to prevent or treat AD and most believe that it is …

Read more

Rapamycin and Two Other Drugs Extends Lifespan Twice As Much As Any Other Drug Combo

A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study led by UCL and the Max Planck Institute for Biology of Aging. The three drugs are all already in use as medical treatments: lithium as a mood stabilizer, trametinib as a cancer treatment and rapamycin …

Read more