Genetically modified pigs as human organ transplantation source

Gene-edited piglets have been cleaned of viruses that might cause disease in humans. There were 33,600 organ transplants last year in the USA, and 116,800 patients on waiting lists and there are around one billion pigs in the world. 100 million pigs are killed each year in the USA for food. A few tens of …

Read more

Youthful Plasticity Restored to the Brains of Adult Mice

The brain loses flexibility with age, impacting the ability to learn, remember, and adapt. Now, scientists at University of Utah Health report they can rejuvenate the plasticity of the mouse brain, specifically in the visual cortex, increasing its ability to change in response to experience. Manipulating a single gene triggers the shift, revealing it as …

Read more

Regenerative nanochip restores ANY tissue with 98% success and clinical trials start next year

Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells. “By using our novel nanochip technology, injured or compromised organs can be replaced. We have …

Read more

‘Origami organs’ can potentially regenerate tissues

Northwestern Medicine scientists and engineers have invented a range of bioactive “tissue papers” made of materials derived from organs that are thin and flexible enough to even fold into an origami bird. The new biomaterials can potentially be used to support natural hormone production in young cancer patients and aid wound healing. The tissue papers …

Read more

Digital to Biological converter for on demand bio

Nature Biotechnology – Digital-to-biological converter for on-demand production of biologics Nextbigfuture covered this a few days ago in a biological teleporter article. Synthetic Genomics has developed a digital-to-biological converter for fully automated, versatile and demand-based production of functional biologics starting from DNA sequence information. Specifically, DNA templates, RNA molecules, proteins and viral particles were produced …

Read more

Pouch of stem cells implanted in trial to cure type 1 diabetes

Viacyte, privately-held, leading regenerative medicine company, announced today that the first patients have been implanted with the PEC-Direct™ product candidate, a novel islet cell replacement therapy in development as a functional cure for patients with type 1 diabetes who are at high risk for acute life-threatening complications. The first implant procedures of the clinical trial …

Read more

Diabetes drug Exenatide shows evidence of slowing progression of Parkisons

A drug commonly used to treat diabetes may have disease-modifying potential to treat Parkinson’s disease, a new UCL-led study suggests, paving the way for further research to define its efficacy and safety. The study, published in The Lancet and funded by The Michael J. Fox Foundation for Parkinson’s Research (MJFF), found that people with Parkinson’s …

Read more

DNA synthesis of virus and bacteria sequences could become a biological teleporter

Synthetic Genomics Inc. (SGI) has a cartful of equipment which they call a biological teleporter. The equipment can print out the entire DNA for a virus or a bacteria in a completely automated process. SGI’s BioXP 3200, a commercial DNA printer, forms the heart of the digital-to-biological converter. When Gibson, sitting in his office, sends …

Read more

Fish embryos successfully cryopreserved, thawed and reanimated 10% of them

Scientists report for the first time the ability to both deep freeze and reanimate zebrafish embryos. The method, appearing in the journal ACS Nano, could potentially be used to bank larger aquatic and other vertebrate oocytes and embryos, too, for a life in the future. In the trials, only about 10 percent of the embryos …

Read more

Research holds Promise for Future Clinical Therapies to Slow Aging

Researchers at Houston Methodist made a surprising discovery leading to the development of technology with the ability to rejuvenate human cells. And that couldn’t be more important for the small population of children who are aging too quickly – children with progeria. Cooke studied cells from children with progeria, a rare condition marked by rapid …

Read more