Metformin could help make Rapamycin life extension safe

Aside from a food intake in laboratory mice that’s about 40 percent fewer calories than normal, however, it’s been found that another way to activate this pathway is with rapamycin, which appears to have a significant impact even when used late in life. Some human clinical trials are already underway exploring this potential. A big …

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Brian Wang will be speaking tomorrow at Transhuman Visions in Piedmont- Oakland

Max More and Natasha Vita-More are the Keynote Speakers of TRANSHUMAN VISIONS 2.0 – EAST BAY, plus there’s 15 other speakers: John Smart, Zoltan Istvan, Monica Anderson, Brian Wang, Linda MacDonald Glenn, Michael Annissimov, Grace Walcott, Hank Pellissier, Gray Scott, Dr. Egil Asprem, Kevin Russell, Brad Carmack, Abelard Lindsay, Andres Watson, Gennady Stolyarov II, Wendy …

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Fully Rejuvanating bodies two to four times for life extension to 180-280 years

Robert Freitas work on using nanomedicine to achieve lives that only end when fatal accidents occur. Robert had a chart that showed the improvement in life expectancy by decade and the sources. Sanitation (1890-1915) Vaccines (1920-1935) Antibiotics.(1940-1960) Notice that none of the big three here were purposely kept from the poor in the developed countries …

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The World is safe for Radical life extension – We can research life extension to rejuvenate the old because we will use technology that is over 100 years old to provide food for over 100 billion people

I was at the Brains events Immortalist Audit event on Saturday. It was a fun and interesting event. There was a question posed at the event. What happens if Radical life extensions happens ? What happens in 50-100 years ? 1. It will take some time for radical life extension to be developed for anyone …

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The most popular articles of Nextbigfuture

Nextbigfuture will be reaching 35 million pageviews at the end of this month and will shortly reach 14000 articles. Nextbigfuture has had 14,500 comments in the last 3 months. The All-time most popular Nextbigfuture articles are 1. Technical hurdles have been overcome for the first human head transplant. [343,000 pageviews, 6100 facebook shares, 346 tweets, …

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How long lives might be extended beyond about 180 years of lifespan matters less than how quickly and how widely improved medicine can be adopted for societal impact analysis

There was a debate between PZ Myers, David Brin, Eliezer Yudkowski and Eneasz Brodski about immortality. Eliezer brought up the point about different levels of immortality and had 10,000 years as a lower bound of immortality. Many of the complaints from PZ Myer and David Brin were concerns about societal effects that might accompany the …

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Monkey head transplant video and spinal repair in dogs and spinal repair in humans

We recently covered a new proposal for the first head transplant in humans. They would use a minimally traumatic cut of the spinal cord using an ultra-sharp blade (very different from what occurs in the setting of clinical spinal cord injury, where gross, extensive damage and scarring is observed) followed within minutes by chemofusion (GEMINI). …

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Technical hurdles have been overcome for the first human head transplant

The project for the first head transplant in man is code-named HEAVEN/GEMINI (Head Anastomosis Venture with Cord Fusion. UPDATE – Welcome Reddit readers. This article made the front page of reddit. Thanks for the upvotes. UPDATE – I cover the internet and news reactions to this article and added technical information. UPDATE I consider this …

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DARPA’s lightweight soft exoskeleton the Warrior Web is revealed

DARPA has released a video of a soldier carrying a 61-pound load while walking in a prototype DARPA Warrior Web system during an independent evaluation by the U.S. Army. It is less like the hard exoskeleton of Iron man and more like the supersuit of the Pixar Incredibles. Warrior Web seeks to create a soft, …

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Ten million H1NI flu vaccines produced in one month, says DARPA

A DARPA-funded vaccine company working on ways to quickly develop immunizations for potential pandemics, has successfully made over 10 million doses of H1N1 flu vaccine in a single month. The company, Medicago Inc., used a “rapid-fire,” plant-based production method to make them, according to DARPA. The plants used in this case, however, aren’t factories, but …

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