disease Archive

diseaseSingle-nucleus RNA sequencing, droplet by droplet

DroNc-Seq — a technology that merges single-nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues. Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This system enabled researchers to study …

diseaseOffshore vaccine tests to shortcut FDA delays

Peter Thiel is backing the offshore testing of an experimental herpes vaccine. Thiel invested $7 million in the ongoing vaccine research, according to the U.S. company behind it. Southern Illinois University also trumpeted the research and the study’s lead researcher, …

diseaseGene therapy cures Duchenne muscular dystrophy in dogs

Duchenne muscular dystrophy (DMD) is an incurable X-linked muscle-wasting disease caused by mutations in the dystrophin gene. Gene therapy using highly functional microdystrophin genes and recombinant adeno-associated virus (rAAV) vectors is an attractive strategy to treat DMD. Here we show …