Genome Editing Anti-cancer System

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The system, called CRISPR-LNPs, carries …

Read more

Commercial Molecular Electronics Chips in 2021

Roswell Biotechnologies and IMEC are partnering to develop the first molecular electronics chips for disease surveillance, precision medicine and DNA storage. They are targeting 2021 for commercial molecular electronic chips. In 2018, IMEC and Candence taped out a 3 nanometer precision test chip. IMEC also has onchip fluid sensors and tiny sensors for internet of …

Read more

Human Gene Editing of Embryos Will Be Safe and Effective Within Two Years

Safe production of gene-edited babies could be possible in just one or two years, and the head of China’s leading genetic research program says the need is now urgent for international regulations. Professor Yang Hui said his team had achieved a major breakthrough, tripling the efficiency of a new gene editing tool that can modify …

Read more

Better Gene Editing than CRISPR

George Church describes going beyond cutting DNA to precise editing. 1. Phage Integrases (Protein and DNA) 2. TAL Deaminases (custom Protein) 3. Chemical Targeting (custom polymer) 4. lambda (λ)-red recombinase (Custom DNA) Beyond editing to writing large genomes DNA-based target recognition For DNA-based target recognition systems, the two major approaches, multiplex automated genome engineering (MAGE) …

Read more

Human Gene Editing Scientist Does Not Face Death Penalty Risk

Robin Lovell-Badge, Ph.D., a geneticist at The Francis Crick Institute, said Chinese scientist He Jiankui contacted him to deny there was a death penalty risk for his editing of human embryos. Lovell-Badge had speculated on January 7 that He could receive the death penalty for bribery and corruption because he disregarded official government oversight of …

Read more

Science on track to identifying genetics of intelligence within 5 years

Gene-based analyses found 536 genes significantly associated with general cognitive function; many were highly expressed in the brain, and associated with neurogenesis and dendrite gene sets. Genetic association results predicted up to 4% of general cognitive function variance in independent samples. There was significant genetic overlap between general cognitive function and information processing speed, as …

Read more