Antiaging expert Aubrey de Grey says antiaging science is considerably closer to robust mouse rejuvenation than we were 10 years ago and the gap between the achievement of robust mouse rejuvenation and the achievement of robust human rejuvenation is also coming down quite fast. Aubrey de Grey is the co-founder of the SENS research foundation …
There are two huge aspects to a new antiaging drug. The first aspect is that a large portion of age-related brain decline is not permanent damage. This non-permanent damage is repaired overnight by a new antiaging drug. The Google-back antiaging company, Calico, has licensed the drug. A new University of San Francisco antiaging drug, called …
AgelessRx claims that PEARL is the first nationwide telemedicine trial and one of the first large-scale intervention trials on Longevity. The human trial is a stepping stone to the way to bringing rapamycin to the Longevity market. PEARL (Participatory Evaluation of Aging with Rapamycin for Longevity) is a $600,000 trial with the University of California. …
As you get older, key genes that maintain life are no longer activated. George Church is focused on turning youth-boosting genes back on. His company, Rejuvenate Bio, has begun clinical trials in old dogs. This will help us determine which ages of humans would best benefit. George believes they will be able to help people …
There are iconic looks for different decades. There was changing fashion, cars and devices that we carried. The look of the 1950s was immortalized in the movie American Graffiti and the TV show Happy Days. The iconic cars were early station wagons, convertibles, Studebakers, Hudson cars, motorcycles. There was a high percentage of kids because …
Life expectancy by year from 1900 to 2000 in the US had the following changes. From 1900 to 1920 life expectancy went from 47 to 54. From 1918 to 1921 life expectancy went from 39 to 60 WW1 and Spanish flu had a lot of youthful deaths that drove down the average age of death …
Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. These pathways are also in …
George Church indicates Rejuvenate Bio is working toward combination gene therapy against 300+ human genes that effect aging. There is also progress in super-resolution imaging of chromosomes and hyper-detailed tissue analysis. They will be able to analyze the DNA in the chromosome without breaking it up and knowing the exact position of the DNA. Microscopic …
The UN population projections assume that world lifespans increase from 72.6 today to 77 in 2050 and then about 82 in 2100. There are already populations that have life expectancy over 92 years. Asian American women in New Jersey life the longest. Decent genetics, near-optimal lifestyle and good healthcare can enable a life expectancy of …
Nextbigfuture has been eagerly awaiting the publication of the research paper on the scientific results of the combination gene therapy experiments by George Church and the team at Rejuvenate Bio. There was a video over one year ago where George Church mentioned being able to double the lifespan of mice. This would be three times …
In his talk at Ending Age-Related Diseases 2019, Estimating the True Complexity of Comprehensive Rejuvenation, SENS founder Aubrey de Grey talks about the intricacies of creating a complete rejuvenation biotechnology framework, including the differing rates of age-related damage and the ramifications of the extensive crosstalk between different types of this damage. The reason for grouping …