Identifying Decades from the 1950s to the 2030s

There are iconic looks for different decades. There was changing fashion, cars and devices that we carried. The look of the 1950s was immortalized in the movie American Graffiti and the TV show Happy Days. The iconic cars were early station wagons, convertibles, Studebakers, Hudson cars, motorcycles. There was a high percentage of kids because …

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One Plus One Cellular Modification Gives Five Times the Anti-aging Effect in Worms

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. These pathways are also in …

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Combination Gene Therapy Progressing Against Aging

George Church indicates Rejuvenate Bio is working toward combination gene therapy against 300+ human genes that effect aging. There is also progress in super-resolution imaging of chromosomes and hyper-detailed tissue analysis. They will be able to analyze the DNA in the chromosome without breaking it up and knowing the exact position of the DNA. Microscopic …

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Demographics and the Transition to Over 200 Year Lifespans

The UN population projections assume that world lifespans increase from 72.6 today to 77 in 2050 and then about 82 in 2100. There are already populations that have life expectancy over 92 years. Asian American women in New Jersey life the longest. Decent genetics, near-optimal lifestyle and good healthcare can enable a life expectancy of …

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George Church and Rejuvenate Bio’s Combination Gene Therapy Paper

Nextbigfuture has been eagerly awaiting the publication of the research paper on the scientific results of the combination gene therapy experiments by George Church and the team at Rejuvenate Bio. There was a video over one year ago where George Church mentioned being able to double the lifespan of mice. This would be three times …

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Aubrey Updates on Antiaging Progress and Timing

In his talk at Ending Age-Related Diseases 2019, Estimating the True Complexity of Comprehensive Rejuvenation, SENS founder Aubrey de Grey talks about the intricacies of creating a complete rejuvenation biotechnology framework, including the differing rates of age-related damage and the ramifications of the extensive crosstalk between different types of this damage. The reason for grouping …

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Longevity Biotech Startup Success and What Antiaging Success Might Look Like

In June 2019 at the Ending Age-Related Diseases 2019, James Peyer of Kronos BioVentures gave a talk about the investment aspects of rejuvenation biotechnology. He explained the effects of the population pyramid, showing the audience why cures for age-related diseases are such a necessity, and comparing population projections. One hundred years ago, the three leading …

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Rapamycin and Two Other Drugs Extends Lifespan Twice As Much As Any Other Drug Combo

A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study led by UCL and the Max Planck Institute for Biology of Aging. The three drugs are all already in use as medical treatments: lithium as a mood stabilizer, trametinib as a cancer treatment and rapamycin …

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