RNA Archive

businessWhat is hot in multi-billion dollar RNAi, Gene therapy and CAR-T biotech?

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There were two biotech buyouts this week. Celgene bought CAR-T player Juno Therapeutics for $9 billion and Sanofi buying blood disorder biotech Bioverativ for $11 billion. Kite Pharmaceuticals, CAR-T company, got acquired late in 2017 by Gilead for $12 billion. …

crisprRNA editing with CRISPR-Cas13

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New Broad Institute ‘REPAIR’ system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome. The Broad Institute and MIT scientists who first harnessed CRISPR for mammalian genome editing have engineered a new molecular system …

medicineSmall RNA could be breakthrough cancer treatment with a cancer kill switch

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Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a …

diseaseSingle-nucleus RNA sequencing, droplet by droplet

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DroNc-Seq — a technology that merges single-nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues. Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This system enabled researchers to study …

futureViome for managing your microbiome

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There are approximately 40 trillion microorganisms living in your gut. They help you digest your food, produce beneficial and harmful chemicals, control infections by pathogens, regulate your immune system, and even control your emotions (ever have a gut feeling?). These …

crisprCRISPR is used to eliminate toxic RNA which could treat RNA related diseases

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CRISPR DNA editing is allowing correction of many diseases. But many other diseases are linked to RNA. Biotech startup Locana is using the power of CRISPR to develop treatments for disease caused by RNA. They use a technique for tracking …

DNA nanotechnologyRNA circuits transform cells into nanodevices with 12 input logic

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In new research, Alex Green, an assistant professor at ASU’s Biodesign Institute, demonstrates how living cells can be induced to carry out computations in the manner of tiny robots or computers. The results of the new study have significant implications …

biotechnologyCircular RNAs can communicate with ribosomes and make proteins

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For decades, loops of genetic material known as circular RNA were considered a kind of genetic accident. But scientists have given them new attention in recent years, and a set of papers published this month suggests some of them actually …

DNAFourth Yangjiang unit enters commercial operation

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Unit 4 of the Yangjiang nuclear power plant in China’s Guangdong province has completed commissioning tests and now meets the conditions for entering commercial operation, China General Nuclear (CGN) announced on March 15, 2017. The loading of fuel assemblies into …

darpaChina activating J-20 stealth fighters now in advance of South Korea getting 40 F-35s in 2018

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China’s state media reports that that the fifth-generation J-20 stealth fighter has been put into active military service and this is two years earlier than previously expected. China’s military has not confirmed this. Military insiders said the appearance of J-20s …