Longeveron developing stem cell treatments for Frailty, Alzheimers and other aging diseases

Longeveron is a life sciences company developing biological solutions for aging and aging-associated diseases through the use of Allogeneic Human Mesenchymal Stem Cells, harvested and grown at our facility in Miami, Florida, from adult-donor bone marrow. Longeveron is a privately funded startup. The Longeveron-grown Mesenchymal Stem Cells (LMSCs) are multipotent stem cells. Mesenchymal stem cells, …

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Platelet coated stem cells Could Offer Targeted Heart Repair

Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury – and getting them to stay there – remains challenging. In a new pilot study using an animal model, North Carolina State University researcher Ke Cheng and his team show that “decorating” cardiac …

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Human skeletal muscle grown from stem cells

Biomedical engineers have grown the first functioning human skeletal muscle from induced pluripotent stem cells. The advance builds on work published in 2015 when researchers at Duke University grew the first functioning human muscle tissue from cells obtained from muscle biopsies. The ability to start from cellular scratch using non-muscle tissue will allow scientists to …

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US Army improving the regrowth of bone, muscle and skin

US Army researchers are using fillers to bridge the gap in damaged bones, hoping to figuratively bridge the gap between current regenerative techniques and the ideal: people regrowing lost limbs. Stephanie Shiels with the U.S. Army Institute of Surgical Research, Fort Sam Houston, Texas, talked about her research to develop a synthetic bone gap filler …

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Engineered Stem Cells repaired spinal cords in 5 out of 12 Rats

Engineered human stem cells have been used to enable paraplegic rats to walk independently and regain sensory perception. The implanted rats had some healing in their spinal cords. Led by Dr. Shulamit Levenberg, of the Technion-Israel Institute of Technology, the researchers implanted human stem cells into rats with a complete spinal cord transection. The stem …

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Tissue engineering, replacement organs and regenerative medicine are getting friendlier regulations

The FDA (Food and Drug Administration) is rolling out a new “regulatory framework” aimed at encouraging and speeding legitimate development of regenerative therapies. The FDA intends to promote the “least burdensome” rules for companies big and small that are seeking to develop new therapies, “while ensuring patient safety.” “Our policy will allow product manufacturers that …

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Regeneration of the entire human skin using transgenic stem cells

Epidermolysis bullosais is rare, but the charity DEBRA, which campaigns for EB patients, estimates half a million people are affected around the world. There are different forms of epidermolysis bullosa, including simplex, dystrophic and, as in this case, junctional. Each is caused by different genetic faults leading to different building blocks of skin being missing. …

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Breakthrough Gel for growing large quantities of neural stem cells

There is a solution to the dual challenges of growing and preserving neural stem cells in a state where they are still able to mature into many different cell types. The first challenge is that growing stem cells in quantity requires space. Like traditional farming, it is a two-dimensional affair. If you want more wheat, …

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Vigorous Hair Growth from stem cells could treat baldness

USC researchers have grown hair follicles from skin cells reproduced in vitro in the lab. Researchers outline a step-by-step sequence of events in the production of hair follicles from skin. Specifically, they were able to generate hair by uncovering the major molecular events necessary for the growth of skin and fostering it in adult shaved …

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Synthetic DNA coverts stem cells to heart muscle is potential tissue regeneration treatment

A newly discovered DNA-targeting molecule could inspire the first tissue regeneration therapies. The synthetic molecule can cause stem cells to transform into heart muscle cells. The scientists responsible for the new molecule believe their breakthrough could be used to turn stem cells into a variety of cell types — paving the way for tissue regeneration. …

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Nerve Cells restored in Monkeys with Parkinsons like disease

Parkinson’s disease causes the progressive loss of nerve cells that release dopamine, a chemical that helps control body movement. The researchers triggered a similar loss of cells in macaque monkeys, then used human stem cells to replace them. They hope to have human clinical trials in 2018. The animals showed significant improvement in their symptoms …

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