The End of Aging is Near (Part 2)

Guest article by Jason Hope.

Despite all the advances in medical science, man has yet to cure any age-related diseases. Heart disease, cancer, diabetes, and other illnesses continue to ravage our bodies while we grow old, despite the best efforts of our doctors and mountains of medicine.

The SENS Research Foundation, or SRF, hopes to change all that. Through continued collaborative research, education and outreach, SENS will continue to build the industry that permanently eradicates old-age diseases. SRF establishes a path that leads us from where we are today, a time where the scientific community has the wherewithal to lay out a detailed plan like this one, to a tomorrow when prototype therapies reduce the signs of aging in laboratory mice. Because mice experience many of the same aging processes as humans do, negligible senescence in humans is possible.

Reaching for negligible senescence through anti-aging strategies has real-world applications that go far beyond reducing wrinkles and sagging skin in old people. Age-related illnesses, like heart disease, cancer and diabetes are debilitating and expensive. The increases in cost and decrease of quality of life will become more profound as a growing number of people live longer. Without a clear-headed approach to negligible senescence, the aging process will cripple an increasing population worldwide.

Building on past collaborative efforts between SRF and the University of Chicago, the SENS foundation works with University of Denver to expand the widely used International Futures forecasting system that predicts how extending lifespan will affect the nation. This project encourages us all to think broadly about the consequences of increasing human longevity.

SRF has many ongoing projects already in motion that will carry us to tomorrow’s anti-aging technology. Researchers at the Albert Einstein College of Medicine in Bronx, New York will be able to control epimutations, which is the permanent DNA damage cells suffer while we grow old. SENS research will help doctors prevent cardiovascular disease before it happens, disrupt the growth of cancer cells, and preserving the energy-producing abilities of mitochondria.

Many SRF research projects will focus on the seven specific types of damage that cause the human body to deteriorate identified by SRF founder Aubrey de Grey. SRF research will someday cure:

• Cell loss or atrophy without replacement
• Oncogenic nuclear mutations and epimutations
• Cell senescence, or death-resistant cells
• Mitochondrial mutations
• Intracellular junk or junk inside cells
• Extracellular junk or junk outside cells
• Random extracellular cross-linking

Research like this is not cheap but not altogether expensive. If fully funded to a level of $100 million annually, a drop in the bucket compared to the National Institution on Aging’s budget, SENS research is a ten to twenty year project. Donations fund the creation of a large research community and public support. In the end, SRF will develop a functional toolkit to end aging.

The founder, researchers, administrators, students, and volunteers associated with SRF will continue to work together to end illness, disability and early death associated with the aging process. Together, we can permanently eradicate debilitating age-related illnesses, increase lifespan and dramatically improve the quality of life. Contact SRF to learn how you can be a part of the future of aging.

Part 1 is at this link

Bio of Jason Hope

Jason Hope is an entrepreneur, futurist, philanthropist, and investor located in Scottsdale, Arizona with a passion for technology and giving back to his community. As an Arizona native, Jason grew up in Tempe and received a degree in finance from Arizona State University, and an MBA from ASU’s W.P. Carey School of Business. Along with his philanthropic and business initiatives, Jason has a dedicated interest in politics as related to business throughout the state of Arizona as well as nationally.

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