I started taking Rejuvant time released AKG almost three months ago. AKG is safely used by millions for bodybuilders and athletes. Time-released AKG from Rejuvant is used for healthier aging. Midway-through the six month trial, I am feeling healthy but I will not be able to see the biological impact until I get results from the second aging biomarker test.
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https://rejuvantsale.com/
Use code BIGFUTURE for a discount.
I started with an aging biomarker test and a spit test analysis. The analysis found that I had genetics that reduced my absorption of Vitamin B. My biological age was 6 months less than my physical age (almost 58). I am now taking Vitamin B supplements along with Rejuvant. I will taking another aging biomarker tests after the six months of Rejuvant. If I was like the average of a previous study, I would expect to see about an eight year reduction in the aging biomarker.
Rejuvant has human medical studies where aging biomarkers have been reversed to reduce measured biological age. There is more than the single case as the study looked at hundreds of people.
This chart shows the measurements. There are error bars but the midpoints indicate that over a three 6 months courses of using Rejuvant every day he has his measured biological age reduce from 52 down to 45. Tom Weldon is 67 years old. If this is accurate, then it would suggest he is squaring the health curve. According to biomarkers he is getting substantially healthier.
I would interpret effect to mean that people can be far healthier up to 80 to 95 but then aging damage still reaches critical levels to cause aging diseases.
I would cite the example of the fitness guru, Jack LaLanne. Jack was fanatical about eating right and exercising. Jack has amazing feats of fitness into his 80s. National University of Singapore to study this as part of means to achieve a five-year increase in healthspan for all people in Singapore. Kennedy is collaborating with Rejuvant.
Brian Kennedy indicates he agrees with the Aubrey dr Grey / SENS analysis of seven kinds of aging damage.
Deep omics (genomics and epigenics) data to personalize these supplements and repurposed drugs and other interventions for optimal healthspan extension in middle-aged participants.
One of the supplements is alpha-ketoglutarate, which has been shown to increase the healthspan – the period of life spent in good health – and lifespan in mice. The centre will be investigating whether six months of daily supplementation can slow biological aging and initial results are estimated to be available in a year’s time, said Professor Andrea Maier, the centre’s co-director. Repurposed drugs include metformin, a well-known drug used to treat Type 2 diabetes, that may be able to slow ageing.
Extended healthspan in older adults is possible through strength training exercise.
Professor Brian Kennedy, internationally recognized for his research into the biology of aging and for his work to translate research discoveries into new ways of delaying, detecting, and preventing human aging and its associated diseases, is helming the Centre with co-director, Professor Andrea Maier, an internal medicine specialist renowned for translational research in aging and age-related diseases diagnostics and pharmacological and non-pharmacological interventions in aging humans.
The 1,600 square feet Centre for Healthy Longevity (CHL) located at Alexandra Hospital, will conduct trials and execute validation studies with healthy participants from the age of 30 years. The Centre will develop and test these interventions using newly identified biomarkers of human aging.
CHL will be looking at blood-based biomarkers, probably the most investigated group due to the large amount of data accumulated in clinical trials.
Many Well Funded Efforts
There are many well funded antiaging efforts. Saudi Arabia has the Hevolution fund which invests $1 billion every year into antiaging.
There are over 158 companies working on antiaging. There are over 340 clinical trials. They have a market cap of over $6 billion. They have over $10 billion in funding. There are over 5000 employees at the antiaging companies.
Brian Wang is a Futurist Thought Leader and a popular Science blogger with 1 million readers per month. His blog Nextbigfuture.com is ranked #1 Science News Blog. It covers many disruptive technology and trends including Space, Robotics, Artificial Intelligence, Medicine, Anti-aging Biotechnology, and Nanotechnology.
Known for identifying cutting edge technologies, he is currently a Co-Founder of a startup and fundraiser for high potential early-stage companies. He is the Head of Research for Allocations for deep technology investments and an Angel Investor at Space Angels.
A frequent speaker at corporations, he has been a TEDx speaker, a Singularity University speaker and guest at numerous interviews for radio and podcasts. He is open to public speaking and advising engagements.
I hope that the biomarker test facility you use is completely separated and independent from the company selling the compounds you are taking. Cheating with the results will be a sure way of generating more business by using all the customers as influencers.
Forget that guy. There are many of us who appreciate all your hard work in keeping us apprised of all the advancements happening around us. I am 68 and my DNA test said I’m 57. Heart scan said my heart is 40 to 44 years old. I work out everyday and take a fistfull of supplements. I can’t wait to see your 6 month results. I get my next test in August. Life is an adventure if you have the right perspective. Thank you Brian is what needs to be said.
I’m curious about what happens if, say, you take a AKG antiaging supplement for 6 months and then stop taking it. Do you regress? How long do the antiaging effects last after you stop taking it?
Also there are other antiaging supplements being touted, most recently the amino acid Taurine. Do they compound or do they diminish each of their antiaging effects?
I believe supplementation will have positive effects but there is much that we don’t know.
Please keep us informed about your 6 month test results. I’m sure I’m not alone in being skeptical of this product in the real world with real people, and your experience will help me (us) make an informed decision.
At $135/30 day bottle, Rejuvant is pretty expensive, as supplements go. Is it worth depends on one’s budget as well as one’s desire/need to live a longer, healthier lifespan (these two things are not the same).
I looked at it, and it’s a combination of the calcium salt of Alpha-Ketoglutarate, (In time release form, though.) and vitamin A in relatively normal quantities. And buying it gets you an occasional aging test.
I think the vitamin A is kind of pointless if you’re already supplementing, and it’s not the most cost effective way to buy those aging tests. And buying C-AKG bulk is a LOT cheaper. But I’m having trouble finding any other source of time release AKG. They claim that the time release aspect is quite important because the stuff is metabolized rapidly and so timed release is the only way to get a sustained level in your system.
I think that’s at least plausible. And the science on it being anti-aging seems good, too.
It’s about $100 a month, which is about twice what I’m paying for all my other supplements put together, and I know for sure I need at least the SAMe, which is most of that. (It’s the only thing holding my arthritis at bay.) But if it works as they claim, it would be worth it.
I’ll be waiting to hear of Brian’s second test. In the meanwhile, I might just get some C-AKG to dissolve in my water jug, so as to at least get manual timed release during the day.
LongJuvity Labs has a timed release CaAKG product on Amazon that is much more affordable than the product Brian is taking.
So they do. Not a bad price. Guess I’ll be adding that to my regimen after all.
“vitamin A in relatively normal quantities” i beg to disagree with your opinion. For a person who is allergic to vitamin A (depression and suicide attempts after that) the dose of vitamin A in Rejuvant is lethal. Another drawback, for someone who reacts badly to calcium, a dose of calcium in Rejuvant (which slows down the release of AKG) also causes serious side effects. If he/she is with athersclerosis, in longer term it als can be lethal. Generic CaAKG in bulk cost around $50-75 per 100 grams (6 to 9 times cheaper per gram). Less frequent taking of Rejuvant doesn’t justify extra costs, even without it’s lethal drawbacks.
I read this paper that was very persuasive that we are being poisoned by Vit. A overdoses. Read this and see if it does not at least make sense. Vit’s A is now added to all sorts of stuff. Milk, cereal, they are putting it in everything. He tracked VERY LARGE population trends that directly relate the increase in Vit. A dosage and a myriad of diseases.
Connecting Eczema, Crohn’s and Alzheimer’s
https://ggenereux.blog/2015/02/12/eca/
Now here’s what’s super interesting about this paper. He has linked over use of Vitamin A with all these diseases. He makes a fairly good case for it. One of the really big clues is,
“…Decreasing incidence of inflammatory bowel disease in Eastern Canada: a population database study.
The key observations here are:
A remarkable ~35% drop in Crohn’s disease over this time period (1996-2009)
A stunning ~50% drop in Alzheimer’s mortality over this time period ( 2000-2011)…”
This he linked to the collapse of the Eastern Canadian fisheries and the removal of these very high vitamin A level dish from the diet. He gives many other large population studies that show similar disease trends related to excess vitamin A intake.
What popped out in my mind as another influence is a question I have asked over and over. It’s seems such a mystery to me why some people seem to do very well on a vegetarian diet and some don’t. Maybe this is the answer. If a first world wealthy person goes on a vegetarian diet they could have problems due to a eating a large amount of salads and vegetables with high vitamin A. A person in a less developed area would be more likely to eat a vegetarian diet with much less vitamin A. Maybe more starches as a mainstay of of their diet. This would explain the good health results from the two widely different diets. More meat might mean less vitamin A corresponding to good health with a no carb diet. Could it not be the carbs but the extra vitamin A fortified foods in the diet? Poor people on heavy strach diets seem to be very healthy.
It is not a fact that carbs are bad. I don’t understand it, but some people eat total carb diets and have great health. And some eat next to none and have great heath. A caveat, it should be noted the Eskimos at mostly meat and fat but aged very fast. It seems that the mix is a problem and we don’t really know what mix or why. It’s a big mystery. Maybe Vit. A overdose is the key.
How much compensation do you receive for pushing overly expensive supplements?
I get 10% compensation and I get my readers a 10% discount. Why do you have to choose to be so rude? Do you fear advertising. Advertising is everywhere. Do you want to send messages to the TV stations and radio station to get rid of advertising. You do not have to buy anything. Are you afraid that your weak mind will be influenced. Let me help you. Don’t buy anything. I will turn 58 this year. I am taking the supplements to see if I can avoid or mitigate the inevitable. I wrote an article that I would be experimenting more with antiaging treatments as the decline will accelerate a lot in my 60s and beyond.
You’re right Brian. No reason to get rude. Running a website isn’t cheap and we all look for income streams. Sometimes advertising and clicks, sometimes affiliate networks and a percentage per buy and so on. Nothing wrong with that.
That said, I’m personally waiting to see what results you end up getting.
Keep posting about it.
Sorry the link I posted earlier doesn’t work. I can’t edit it now.
It was missing the last number. This should be it.
https://www.science.org/doi/10.1126/science.abn9257
Here is a less expensive way to try your hand at anti-aging supplements:
https://www.science.org/doi/10.1126/science.abn925
The journal Science just published a cool study called “Taurine deficiency as a driver of aging”
They gave taurine supplements to mice, monkeys and worms. It extended all their lifespans.
10 percent for male mice, 12 for female mice. Its a good read.
Aside from dietary sources, microbes are the sole source of Vitamin B12 synthesis in humans. In C57BL/6 mice, B12 impairs Bacteroides populations [PMID 31062653]. Oral cobalamins can stimulate inflammatory porphyrin production by commensal bacteria [PMID 31941813], [PMC6049814], [PMID 26109103] though this has only been studied to a very limited extent in G.I. flora subject to oral cobalamin.
Just looking at c. elegans experiments, supplementation of folates in longevity is quite complex [PMID 35053330], [PMID 26876180], [PMC8190293].
The only viable aging biomarker is the amount of pathogens, fats and heavy metals in your system. They increase as we age and are responsible for how well our liver function and in general to almost all of our ailments. Our genetics is almost always fine. Fortunately for us we clear our body from this malignants, starting with our diet.
According to the revelations of the Medical Medium.