Altos Labs is working on antiaging with perhaps $270 million raised from billionaires Jeff Bezos and Yuri Milner and others. Securities disclosure filed in California in June indicates Altos has raised at least $270 million. Scientists joining Altos: Juan Carlos Izpisúa Belmonte, a Spanish biologist at the Salk Institute, in La Jolla, California.Juan researched mixing …
Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of genetic and drug treatments to prevent memory loss in people as they age. The team have already identified a potential drug, licensed for human use, that can be taken by mouth and …
Pulsechain has raised $25,000,000 for antiaging medical research after 5 days of a 14 day fundraiser. You must follow the SENS.org PulseChain instructions. Sacrifices to SENS.org during the sacrifice phase earn 25% less points compared to sacrifices at Pulse.info. SENS.org can also accept stocks and bank wires. Once the sacrifice phase is over, the total …
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer’s disease, but also reverse the effects of the disorders. The team, based at Tohoku University, published their results on June 8 in the International Journal of Molecular Sciences. The treatment candidate has been …
Zoledronate is a biophosphonate, a drug used to strengthen bones and reduce the risk of osteoporosis-related bone fractures. It is well-absorbed into the bones, so it only needs to be administered through infusion once a year. A 2010 study had found that people who were given zoledronate after experiencing hip fractures showed slightly reduced all-cause …
Antiaging gene therapies to overexpress TERT and Follistatin were used in a mouse model. The mice saw a 41 and 32% increase in median life span. The study also used a novel viral vector, cytomegalovirus for the delivery. Liz Parish of Bioviva has treated herself with all of these antiaging gene therapies. If humans experienced …
David Sinclair is a geneticist at Harvard and author of Lifespan. Nature – Reversal of biological clock restores vision in old mice Sinclair and his team restored vision in old mice and in mice with damaged retinal nerves by resetting some of the thousands of chemical marks that accumulate on DNA as cells age. They …
GERO.AI uses Whole-Exome Sequencing data for in-human AI Drug Discovery, while GeroSense is the arm of Gero creating Digital Biomarkers. GERO.AI models are taken from the physics of complex dynamic systems. They have presented their unique approach in the journal Frontiers in Genetics. They combine deep neural networks with the physical models to study dynamical …
Rapamycin has been proven to extend the lifespan of mice, warms and yeast. Lifespan.io is starting a large clinical trial named Participatory Evaluation (of) Aging (with) Rapamycin (for) Longevity Study, or PEARL, to see if the antiaging effects of Rapamycin apply to humans. This will be the first study to see if Rapamycin works as …
There is a new gene-editing tool called Retron Library Recombineering (RLR) that makes this task easier that has been developed by George Church and his team. RLR generates up to millions of mutations simultaneously, and “barcodes” mutant cells so that the entire pool can be screened at once, enabling massive amounts of data to be …
People who live beyond 105 years are more efficient at repairing DNA, according to a study published today in eLife. Paolo Garagnani and colleagues, in collaboration with several research groups in Italy and a research team led by Patrick Descombes at Nestlé Research in Lausanne, Switzerland, recruited 81 semi-supercentenarians (those aged 105 years or older) …
