New Antiaging Lab Altos Gets $270+ Million in Funding

Altos Labs is working on antiaging with perhaps $270 million raised from billionaires Jeff Bezos and Yuri Milner and others. Securities disclosure filed in California in June indicates Altos has raised at least $270 million. Scientists joining Altos: Juan Carlos Izpisúa Belmonte, a Spanish biologist at the Salk Institute, in La Jolla, California.Juan researched mixing …

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$25 Million Raised for SENS Antiaging Research Via Pulsechain Crypto Drive

Pulsechain has raised $25,000,000 for antiaging medical research after 5 days of a 14 day fundraiser. You must follow the SENS.org PulseChain instructions. Sacrifices to SENS.org during the sacrifice phase earn 25% less points compared to sacrifices at Pulse.info. SENS.org can also accept stocks and bank wires. Once the sacrifice phase is over, the total …

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Success in Reversing Dementia in Mice and Human Clinical Trials in 2022

Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer’s disease, but also reverse the effects of the disorders. The team, based at Tohoku University, published their results on June 8 in the International Journal of Molecular Sciences. The treatment candidate has been …

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Off-Patent Osteoporosis Drug Also Found to Extend Lifespan

Zoledronate is a biophosphonate, a drug used to strengthen bones and reduce the risk of osteoporosis-related bone fractures. It is well-absorbed into the bones, so it only needs to be administered through infusion once a year. A 2010 study had found that people who were given zoledronate after experiencing hip fractures showed slightly reduced all-cause …

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Antiaging Gene Therapies Extend Lifespan of Mice by 41%

Antiaging gene therapies to overexpress TERT and Follistatin were used in a mouse model. The mice saw a 41 and 32% increase in median life span. The study also used a novel viral vector, cytomegalovirus for the delivery. Liz Parish of Bioviva has treated herself with all of these antiaging gene therapies. If humans experienced …

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Hacking Aging with AI

GERO.AI uses Whole-Exome Sequencing data for in-human AI Drug Discovery, while GeroSense is the arm of Gero creating Digital Biomarkers. GERO.AI models are taken from the physics of complex dynamic systems. They have presented their unique approach in the journal Frontiers in Genetics. They combine deep neural networks with the physical models to study dynamical …

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New Gene Editing Tool for Millions of Edits

There is a new gene-editing tool called Retron Library Recombineering (RLR) that makes this task easier that has been developed by George Church and his team. RLR generates up to millions of mutations simultaneously, and “barcodes” mutant cells so that the entire pool can be screened at once, enabling massive amounts of data to be …

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People Who Live Beyond 105 Have Better DNA Repair

People who live beyond 105 years are more efficient at repairing DNA, according to a study published today in eLife. Paolo Garagnani and colleagues, in collaboration with several research groups in Italy and a research team led by Patrick Descombes at Nestlé Research in Lausanne, Switzerland, recruited 81 semi-supercentenarians (those aged 105 years or older) …

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