Revel Pharmaceuticals engineered an enzyme that removes carboxymethyllysine — a sugar-derived chemical modification of the amino acid lysine — from proteins and restores the residue to normal lysine. It was tested on donated human lens, skin, and arterial tissue in the lab. The significance is that no organism has ever been found with an enzyme …
BerkeleyCAL is convening a select group of scientists, technologists, and global thought leaders at the University of California, Berkeley on May 2nd and 3rd to explore the frontiers of aging, longevity science, and their broader societal impact. The conference will feature a keynote by Her Royal Highness Dr. Haya Al Saud alongside prominent scientists such …
500 fans of a baby-faced beauty key opinion leader (KOL) in China replicated her face through cosmetic surgery at her clinic. She said “After the initial surgeries, my face was uneven and bumpy. Through multiple corrective procedures, I finally achieved the ideal baby face. Half of each year is spent recovering. I’ve endured so much …
vision for healthcare in America Healthcare broken: Americans pay double what other nations for inferior outcomes. Drugs cost 10× more in US. Trump’s demanded most-favored-nation pricing (negotiate lower prices like other countries pay). Pressure pharma without killing innovation (make offers that they cannot refuse). Goal is affordability + access. Think healthcare as investment (extra work …
Elon Musk outlined a vision for Tesla’s Optimus humanoid robots to perform sophisticated medical procedures with superhuman precision, enabling universal access to elite surgical care worldwide. Imagine a world where everyone has access to the best surgeons. Optimus will have the level of precision that is frankly superhuman… There’s a very limited number of great …
Taiwan, South Korea and China have critically low fertility rates below 1.0. Japan is also very low (1.15) and has had low fertility for longer. By 2070, the countries could halve their current populations. A fertility rebound could avert 30-70% of projected population losses by 2100. This might stabilizing societies at near-current sizes—but only if …
South Korea study published in Biomarker Research of 8.4 million adults finds higher risks of overall, lung, prostate, thyroid, gastric, colorectal, and breast cancers — across both mRNA and viral-vector platforms Increased risk for major cancers—such as lung, liver, colorectal, gastric, pancreatic, and breast—typically worsens national life expectancy by elevating age-specific and overall mortality rates. …
Aubrey de Grey describes his plan to get combinations of promising aging damage-repair approaches. Aging is accumulated molecular and cellular damage from metabolism, leading to pathology. He emphasizes that we already know enough to pursue preventative maintenance on the body, which is like maintaining a car for longevity. He highlights progress in startups addressing all …
NASA proposes to pioneer a radically new approach to mitigating radiation-induced cell damage in astronauts by transplanting new undamaged mitochondria (critical radiation-sensitive cell organelles) isolated from each individual pre-exposure. Replacing mitochondria could fix radiation damage and it can fix aging damage. This would help against cardiovascular disease and Alzheimers. There are early voluntary trials of …
Professor Zhang Zhiqian revealed a plan for a Pregnancy Robot in 2026. He has developing pregnancy robots for over 2 years after establishing a corporation in Hong Kong. I don’t believe this has been done. He cites work for premature babies and premature animals. The ethical path to an artificial womb and pregnancy robot would …
In a paper published recently in the journal GeroScience, the UC Irvine team reports that a combination of naturally occurring compounds – nicotinamide (a form of vitamin B3) and epigallocatechin gallate (a green tea antioxidant) – can reinstate levels of guanosine triphosphate, an essential energy molecule in brain cells. In tests on neurons in a …