New Small Molecule Lessens Alzheimer’s Symptoms in Mice

Lifespan.io reports that researchers have reduced memory and learning symptoms in mice. Alzheimer’s research needs new approaches. A paper describes a promising molecule built using a technique that can be expanded to numerous other proteins with post-translational modifications. The researchers were also able to deliver the rather large molecule intranasally across the blood-brain barrier, alleviating …

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Kernel Brain Computer Interface and General BCI Technology Overview

Kernel Working on fNIRS Kernel is building the next generation of brain measurement systems by leveraging the strengths of TD-fNIRS into products that offer the following benefits: High-quality neural signal Full-head coverage Scalability Relatively low cost Natural environments, stimuli, and interactions Freedom of user motion Kernal was founded in 2016 by Bryan Johnson. Kernel has …

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Bill Gates and Bezos Back a Neurolink Competitor

Synchron in a brain computer interface company funded with over $75 million with investors including Bill Gates and Jeff Bezos. Synchron is an implantable brain-computer interface (BCI) company. They published results in medical journal JAMA Neurology of long-term safety results from a clinical study in four patients with severe paralysis implanted with Synchron’s first-generation Stentrode™, …

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Daniel Kraft Updates on Digital Medicine, Medical Apps and Devices

Dr. Daniel Kraft explores the past and future of technology-enabled health and biomedicine and premiers Digital.Health, a new platform for exploring and leveraging existing digital health solutions. For more on the future of health and medicine, join Daniel at NextMed.Health a unique, cross-disciplinary program exploring the cutting edge and future of health(care). Brian WangBrian Wang …

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Definitive Evidence that Vitamin D Halves COVID Deaths and Reduces ICU Admissions

Various studies prove an association between severe vitamin D deficiency and bad COVID-19 outcomes. Other studies show Vitamin D plays a crucial role in immune function and inflammation. Recent data suggests a protective role of vitamin D against bad outcomes. Vitamin D (5000 IU Vitamin D3 daily for 2 weeks) halves the risk of COVID …

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Rejuvenate Bio Reprogrammed Genes to Double Remaining Life of Old Mice

Rejuvenate Bio systemically delivered AAVs (gene therapy delivered via altered virus shells), encoding an inducible OSK system, in 124-week-old mice extends the median remaining lifespan by 109% over wild-type controls and enhances several health parameters. Treated mice lived another 18 weeks, on average, while control mice died in nine weeks. This was a doubling of …

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Manipulating the Epigenome Can Drive Aging and Reverse Aging

Researchers developed a system called “ICE” (inducible changes to the epigenome) in DNA reparation, which actually advances aging, and also discovered that the process can be reversed by using OSK-mediated rejuvenation. Using the ICE system, young mice have aged quickly, but with dire consequences on the tissues in their bodies. Journal Cell – Loss of …

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Overall Annual Global Deaths Will Double Over the Next 60 Years

The UN has their latest world population projections. Overall Annual Global Deaths Will Double Over the Next 60 Years The overall level of absolute annual deaths will be increasing from 60 million per year to about 80 million by 2050 and 100 million by 2070. The annual global death rate will average an increase by …

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Neuralink Day Highlights a Brain Implant With Over 4000 Channels

Neuralink showed off its implantable device which is slightly larger than a quarter. They showed the device working in several monkeys and they showed the surgical robot that will be used to implant the device. They are working to repair spinal damage. The current experiments are to monitor and activate spinal activity in a pig. …

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