Rejuvenate Bio systemically delivered AAVs (gene therapy delivered via altered virus shells), encoding an inducible OSK system, in 124-week-old mice extends the median remaining lifespan by 109% over wild-type controls and enhances several health parameters. Treated mice lived another 18 weeks, on average, while control mice died in nine weeks. This was a doubling of …
Researchers developed a system called “ICE” (inducible changes to the epigenome) in DNA reparation, which actually advances aging, and also discovered that the process can be reversed by using OSK-mediated rejuvenation. Using the ICE system, young mice have aged quickly, but with dire consequences on the tissues in their bodies. Journal Cell – Loss of …
The UN has their latest world population projections. Overall Annual Global Deaths Will Double Over the Next 60 Years The overall level of absolute annual deaths will be increasing from 60 million per year to about 80 million by 2050 and 100 million by 2070. The annual global death rate will average an increase by …
I had previously said that China’s purchasing power parity GDP was likely 30% higher than official numbers. However, purchasing power parity strength does not mean the country would or should do better with a stronger currency. The country has to import 10 million barrels per day in oil. The previous article notes the exchange rate …
Aubrey de Grey announced the expansion of the SenoSTEM project. SENS had the SenoSTEM project. The biggest project of Aubrey’s new foundation will be testing combination antiaging therapies. This is taking antiaging therapies that are beneficial by themselves and using them in combination to hopefully achieve better results. There is a “parabiosis on steroids” project. …
Aubrey de Grey spoke at his Longevity Summit Dublin conference. He has created a new antiaging foundation. They will combine stem cells and senolytic interventions. They will partner with iChor. IChor’s lab is able to perform large mouse studies. They will be able to test many other combinations of aging damage interventions. They will perform …
The leader of the Antiaging movement, Aubrey de Grey, has started a new antiaging foundation. The new foundation will be advancing combination antiaging damage repair therapies. The new foundation will work with Ichor Life Sciences. Ichor spun out of Aubrey’s prior foundation. Ichor has macular regeneration work and has expanded to senenscent cells and acts …
The Great Age Reboot is the concept developed by leading longevity practitioner, Michael Roizen, M.D. (Dr. Mike), Emeritus Chief Wellness Officer at the Cleveland Clinic and best-selling author. Roizen believes that sometime in the next 10 years, you are going to be able to—because of the exponential advances in 14 areas of aging mechanism research—reboot …
the National University of Singapore (NUHS) opens Singapore’s first Centre for Healthy Longevity to increase healthy lifespan of Singapore population by five more disease-free years. The Centre will develop an integrative pre-clinical laboratory model and clinical human research pipeline that focuses on identifying, and treating biological hallmarks of disease. Lien Foundation gifts S$5 million to …
In the MIT Technology Review Celine Halioua, CEO and founder of Loyal a company working on dog longevity said the antiagig field has “suffered from a branding issue” owing to outlandish claims made in the 1990s and 2000s. “Big names [Aubrey de Grey] in the field were yelling about 1,000-year life spans and immortality,” she …
The coming decade will likely see the biggest changes of our lives. These will be bigger than the internet and the smartphone. Brian Wang gave a talk on the future to the Technology Universe Conference. All of the biggest developments for the future will be mostly arriving in a major way over the next decade. …
