Rejuvenate Bio Reprogrammed Genes to Double Remaining Life of Old Mice

Rejuvenate Bio systemically delivered AAVs (gene therapy delivered via altered virus shells), encoding an inducible OSK system, in 124-week-old mice extends the median remaining lifespan by 109% over wild-type controls and enhances several health parameters. Treated mice lived another 18 weeks, on average, while control mice died in nine weeks. This was a doubling of …

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Manipulating the Epigenome Can Drive Aging and Reverse Aging

Researchers developed a system called “ICE” (inducible changes to the epigenome) in DNA reparation, which actually advances aging, and also discovered that the process can be reversed by using OSK-mediated rejuvenation. Using the ICE system, young mice have aged quickly, but with dire consequences on the tissues in their bodies. Journal Cell – Loss of …

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Overall Annual Global Deaths Will Double Over the Next 60 Years

The UN has their latest world population projections. Overall Annual Global Deaths Will Double Over the Next 60 Years The overall level of absolute annual deaths will be increasing from 60 million per year to about 80 million by 2050 and 100 million by 2070. The annual global death rate will average an increase by …

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Better Quality Video of Aubrey De Grey’s Recent Longevity Announcements

Aubrey de Grey announced the expansion of the SenoSTEM project. SENS had the SenoSTEM project. The biggest project of Aubrey’s new foundation will be testing combination antiaging therapies. This is taking antiaging therapies that are beneficial by themselves and using them in combination to hopefully achieve better results. There is a “parabiosis on steroids” project. …

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Aubrey de Grey Announces Tests of Combinations of Aging Damage Interventions

Aubrey de Grey spoke at his Longevity Summit Dublin conference. He has created a new antiaging foundation. They will combine stem cells and senolytic interventions. They will partner with iChor. IChor’s lab is able to perform large mouse studies. They will be able to test many other combinations of aging damage interventions. They will perform …

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Aubrey de Grey New Antiaging Foundation and Combo Therapy Work

The leader of the Antiaging movement, Aubrey de Grey, has started a new antiaging foundation. The new foundation will be advancing combination antiaging damage repair therapies. The new foundation will work with Ichor Life Sciences. Ichor spun out of Aubrey’s prior foundation. Ichor has macular regeneration work and has expanded to senenscent cells and acts …

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Great Age Reboot

The Great Age Reboot is the concept developed by leading longevity practitioner, Michael Roizen, M.D. (Dr. Mike), Emeritus Chief Wellness Officer at the Cleveland Clinic and best-selling author. Roizen believes that sometime in the next 10 years, you are going to be able to—because of the exponential advances in 14 areas of aging mechanism research—reboot …

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Singapore Aging Reversal Center Targets Adding 5 More Healthy Years of Life

the National University of Singapore (NUHS) opens Singapore’s first Centre for Healthy Longevity to increase healthy lifespan of Singapore population by five more disease-free years. The Centre will develop an integrative pre-clinical laboratory model and clinical human research pipeline that focuses on identifying, and treating biological hallmarks of disease. Lien Foundation gifts S$5 million to …

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What is Coming by 2035?

The coming decade will likely see the biggest changes of our lives. These will be bigger than the internet and the smartphone. Brian Wang gave a talk on the future to the Technology Universe Conference. All of the biggest developments for the future will be mostly arriving in a major way over the next decade. …

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