Single cell genomics breakthrough – RNA in single cells sequenced and up to 1000-fold variability in expression levels found
A team of scientists at the Klarman Cell Observatory at the Broad Institute recently completed an effort to read, or sequence, all the RNA — the “transcriptome” — in individual immune cells. Whereas DNA in a cell’s genome represents its blueprint for making the building blocks of cells, RNA is more like the cell’s contractor, …