How the World Defeats Aging by 2035 – Aubrey de Grey Interview

Aubrey de Grey has been the leading voice for antiaging, aging reversal and aging damage repair for over twenty years. He founded the SENS non-profit (Strategies for Engineered Negligible Senescence (SENS). There have been six antiaging companies that have been directly spun out of SENS. SENS is researching the hardest problems related to fixing aging …

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Scientific Progress to Radical Antiaging, Aubrey Sees 50+% of Longevity Escape Velocity by 2035

Antiaging expert Aubrey de Grey says antiaging science is considerably closer to robust mouse rejuvenation than we were 10 years ago and the gap between the achievement of robust mouse rejuvenation and the achievement of robust human rejuvenation is also coming down quite fast. Aubrey de Grey is the co-founder of the SENS research foundation …

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Most Brain Aging Decline Can Be Fixed Overnight

There are two huge aspects to a new antiaging drug. The first aspect is that a large portion of age-related brain decline is not permanent damage. This non-permanent damage is repaired overnight by a new antiaging drug. The Google-back antiaging company, Calico, has licensed the drug. A new University of San Francisco antiaging drug, called …

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Separate Antiaging Trials for Rapamycin and Metformin

AgelessRx claims that PEARL is the first nationwide telemedicine trial and one of the first large-scale intervention trials on Longevity. The human trial is a stepping stone to the way to bringing rapamycin to the Longevity market. PEARL (Participatory Evaluation of Aging with Rapamycin for Longevity) is a $600,000 trial with the University of California. …

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Re-activating Youth Boosting Genes to Reverse Human Aging By 2030

As you get older, key genes that maintain life are no longer activated. George Church is focused on turning youth-boosting genes back on. His company, Rejuvenate Bio, has begun clinical trials in old dogs. This will help us determine which ages of humans would best benefit. George believes they will be able to help people …

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Identifying Decades from the 1950s to the 2030s

There are iconic looks for different decades. There was changing fashion, cars and devices that we carried. The look of the 1950s was immortalized in the movie American Graffiti and the TV show Happy Days. The iconic cars were early station wagons, convertibles, Studebakers, Hudson cars, motorcycles. There was a high percentage of kids because …

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One Plus One Cellular Modification Gives Five Times the Anti-aging Effect in Worms

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. These pathways are also in …

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Combination Gene Therapy Progressing Against Aging

George Church indicates Rejuvenate Bio is working toward combination gene therapy against 300+ human genes that effect aging. There is also progress in super-resolution imaging of chromosomes and hyper-detailed tissue analysis. They will be able to analyze the DNA in the chromosome without breaking it up and knowing the exact position of the DNA. Microscopic …

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Demographics and the Transition to Over 200 Year Lifespans

The UN population projections assume that world lifespans increase from 72.6 today to 77 in 2050 and then about 82 in 2100. There are already populations that have life expectancy over 92 years. Asian American women in New Jersey life the longest. Decent genetics, near-optimal lifestyle and good healthcare can enable a life expectancy of …

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George Church and Rejuvenate Bio’s Combination Gene Therapy Paper

Nextbigfuture has been eagerly awaiting the publication of the research paper on the scientific results of the combination gene therapy experiments by George Church and the team at Rejuvenate Bio. There was a video over one year ago where George Church mentioned being able to double the lifespan of mice. This would be three times …

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