CRISPR gene editing used to cure a mouse of a liver disorder and is the first disease cured in a living animal using CRISPR

Using the new CRISPR gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. the first evidence that this gene-editing technique, known as CRISPR, can reverse disease symptoms in living animals. CRISPR, which offers an easy way to snip out mutated DNA and …

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New silicon anode and a sulfur-based cathode with low fabrication cost and high electrode performance for better rechargeable lithium ion batteries

USC Viterbi School of Engineering professor Chongwu Zhou and his research team have developed a silicon anode and a sulfur-based cathode with low fabrication cost and high electrode performance for rechargeable lithium-ion batteries Researchers at the USC Viterbi School of Engineering have improved the performance and capacity of lithium batteries by developing better-performing, cheaper materials …

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Superforecasting with the Good Judgement Project

For the past three years, Rich and 3,000 other average people have been quietly making probability estimates about everything from Venezuelan gas subsidies to North Korean politics as part of , an experiment put together by three well-known psychologists and some people inside the intelligence community. According to one report, the predictions made by the …

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Eric Drexler Counts Five kinds of nanotechnology and two are not called nanotechnology currently

Eric Drexler counts five kinds of nanotechnology, of which only three are called by that name. Of the three, one is a revolutionary prospect, one is a fantasy, and the third is mostly materials science. As for the other two kinds, one is the heart of today’s greatest technological revolution, while the other is the …

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Investment Manager View of America’s top 1% – Even High Professional Income and Saving does not cut it

An Investment manager has written his view of the top 1% in 2011 and in 2014 The average (median) American family has pre-tax income in the low to mid-$50k range and net worth around $120k. High end professionals at 99 to 99.5 percentile The 99th to 99.5th percentiles largely include physicians, attorneys, upper middle management, …

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Multigeneration Worldship Population Requirements Similar to Battlestar Galactica

According to Portland State University anthropologist Cameron Smith, any 2000 year long Worldship journey would have to carry a minimum of 10,000 people to secure the success of the endeavor. And a starting population of 40,000 would be even better, in case a large percentage of the population died during during the journey. Gardner-O’Kearny calculated …

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For the first time Americans feel they are dropping to lower economic classes as wages kept dropping after the recession

Despite a slowly recovering economy, the proportion of Americans who identify themselves as middle class has dropped sharply in recent years. Today, about as many Americans identify themselves as lower or lower-middle class (40%) as say they are in the middle class (44%), according to a recent Pew Research Center/USA TODAY survey. The findings from …

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Hint of Hope for STAP cells but Hong Kong Researchers says interesting result is only double and needs to be 10 to 100 fold

LA Times reports that just hours after Japanese investigators announced findings of fabrication and misconduct in a highly criticized “acid bath” stem cell study, scientists in Hong Kong said they had partly succeeded in reproducing the controversial experiment, but without acid. Kenneth Ka-Ho Lee, a professor and stem cell scientist at the Chinese University of …

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Ten full sized 3D printed buildings in Shanghai

Back in 2008, University of Southern California Professor Behrokh Khoshnevis said new technology will soon allow massive 3D printers to build entire multi-level houses in under a day. Nextbigfuture covered Contour Crafting in the USA back in 2008 and other companies in Europe who have talked about using large inkjet like printers to use cement …

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High-resolution blueprint for how to build a human brain with genetic details and timing

Researchers at the Allen Institute for Brain Science have generated a high-resolution blueprint for how to build a human brain, with a detailed map of where different genes are turned on and off during mid-pregnancy at unprecedented anatomical resolution. This is the first major report using data from the BrainSpan Atlas of the Developing Human …

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DNA origami make sturdier polyhedra with struts to get them 400 times larger than DNA bricks

Scientists at the Harvard’s Wyss Institute have built a set of self-assembling DNA cages one-tenth as wide as a bacterium. The structures are some of the largest and most complex structures ever constructed solely from DNA. The cage could be modified with chemical hooks that could be used to hang other components such as proteins …

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