Engineered Cas9 Genome-editing protein with 10- to 100-fold increase in specificity
David Liu, and a team of scientists has developed an engineered form of Cas9 that can be turned on with a small drug-like molecule. By using this activatable form of Cas9, the team could modify targets in the human genome with up to 25-fold higher specificity than when using the standard form of Cas9. The …