Quantum computing is now an engineering scaling problem and treating cancer will become like preventing cavities

Vijay Pande, a general partner at Andreessen Horowitz, sees a big shift in Quantum computing. For the last two decades, we had been trying to work out the fundamental science of quantum computing but a lot of the scientific advances are now done. It is now the time for engineering advances. The auestions about how …

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Pen-like Device Accurately Identifies Cancer in 150 times faster

A team of scientists and engineers at The University of Texas at Austin has invented a powerful tool that rapidly and accurately identifies cancerous tissue during surgery, delivering results in about 10 seconds—more than 150 times as fast as existing technology. The MasSpec Pen is an innovative handheld instrument that gives surgeons precise diagnostic information …

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Motorized molecules drill into cancer cells

Motorized molecules driven by light have been used to drill holes in the membranes of individual cells, including cancerous ones. The technique shows promise for either bringing therapeutic agents into the cells or directly inducing the cells to die. Dr Robert Pal at Durham University worked with researchers at Rice and North Carolina State universities …

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FDA approves $475K Leukemia gene therapy treatment with 83% success rate

The Food and Drug Administration on Wednesday announced what the agency calls a “historic action” — the first approval of a cell-based gene therapy in the United States. The FDA approved Kymriah, which scientists refer to as a “living drug” because it involves using genetically modified immune cells from patients to attack their cancer. The …

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US team safely edits dozens of human embryos to correct disease causing genes

The first known attempt at creating genetically modified human embryos in the United States has been carried out by a team of researchers in Portland, Oregon. Three previous reports of editing human embryos were all published by scientists in China. The US work is believed to have broken new ground both in the number of …

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New gene editing screens thousands of genes at once for cancer and will scale to whole genome screening

A novel screening method developed by a team at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center — using CRISPR-Cas9 genome editing technology to test the function of thousands of tumor genes in mice — has revealed new drug targets that could potentially enhance the effectiveness of PD-1 checkpoint inhibitors, a promising new class of cancer …

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Billionaire Jim Mellon invests in Insilico who use deep learning AI to find antiaging drugs

Insilico Medicine, a big data analytics company applying deep learning techniques to drug discovery, biomarker development, and aging research has closed an investment from the billionaire biotechnology investor Jim Mellon. Proceeds will be used to perform pre-clinical validation of multiple lead molecules developed using Insilico Medicine’s drug discovery pipelines and to advance research in deep …

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CRISPR/Cas9 Reveals Cancer’s Synthetic Lethal Vulnerabilities

The CRISPR/Cas9 gene-editing system has been used to identify more than 120 synthetic-lethal gene interactions in cancer cells. These interactions could guide drug developers to new combination therapies that could selectively kill cancer cells and spare healthy cells. Synthetic-lethal gene interactions may occur when certain pairs of mutated genes are present. When there is a …

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Israel may have already used new F35s in January for missile strike in Syria

According to French newspaper Le Figaro, Israel has already put its tiny F-35 Lightning II fleet to use as early as mid-January of this year, having only taken full delivery of the first F-35s in their 75-strong order in mid-December of last year. Reporter Georges Malbrunot, Le Figaro‘s Middle East correspondent, the F-35’s supposed initial …

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Nanoscale simulation of complex logic will enable solution to certain problems that are not suited to binary systems

New nanologic machines consist of individual phosphorous atoms that are precisely positioned and embedded in a silicon crystal at a density of about 200 billion atoms per square centimeter. Single electrons randomly move in and out of the atoms due to quantum tunneling. Since each atom can hold one or two of these electrons, and …

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High-performance, low-energy artificial synapse for neural network computing

A new organic artificial synapse made by Stanford researchers could support computers that better recreate the way the human brain processes information. It could also lead to improvements in brain-machine technologies. “It works like a real synapse but it’s an organic electronic device that can be engineered,” said Alberto Salleo, associate professor of materials science …

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