crispr Archive

cancerCancer cells engineered to trigger a death switch in other cancer cells

Roving cancer tumor cells have been genetically engineered to secrete a protein that triggers a death switch in resident tumor cells they encounter. The cancer-fighting cancer cells also have a built-in suicide switch — so the weaponized cells self-destruct before …

canadaBridged nucleic acids in CRISPR RNAs improves CRISPR gene therapy accuracy by 10,000 times

Canadian research (Alberta) shows that the use of bridged nucleic acids to guide Cas9 can improve its specificity by over 10,000 times in certain instances — a dramatic improvement. Basil Hubbard, Canada Research Chair in Molecular Therapeutics and an assistant …

crisprGene therapy treatment for blood disease approved in Europe

Genetically modification of humans has been been approved for the first time in Europe. Swiss-based biotech company Crispr Therapeutics hope to find a way of curing blood disease beta thalassaemia. China has approved similar gene therapy trials. A trial into …

crisprCRISPR extends lifespan of Lou Gehrigs disease mice by 25%

University of California, Berkeley scientists have for the first time used CRISPR-Cas9 gene editing to disable a defective gene that causes amyotrophic lateral sclerosis, or Lou Gehrig’s disease, in mice, extending their lifespan by 25 percent. The therapy delayed the …

antiagingPersonal CRISPR genetic experimentation

Tristan Roberts is injecting himself with a previously an untested, experimental gene therapy. Several individuals have publicly attempted to augment themselves with genes that will inhibit cell death or boost muscle growth, and self-experimentation is also happening in private. Brian …

biohackingCRISPR muscle boosting gene therapy at few thousand dollars per year will go mainstream

Josiah Zayner is CEO of the biohacking-promoting startup The Odin. He has injected himself with performance enhancing gene therapy to grow larger muscles. He is selling a $20 myostatin inhibitor plasmid. This must be combined with a $300 gRNA in …

crisprMore advanced genomic screening for embyro selection for IVF

In 2014, Nextbigfuture predicted Tiger Moms as being the driver of early adoption of genetic intelligence enhancement and the lifting of the One child policy in China. China’s One child policy was being lifted just as embryo selection based upon …

agricultureCRISPR gene editing technology freely available for agricultural research

On October 18, 2017, DuPont Pioneer and the Broad Institute of MIT and Harvard reached an agreement to jointly provide non-exclusive licenses to foundational CRISPR-Cas9 intellectual property under their respective control for use in commercial agricultural research and product development. …

crisprRNA editing with CRISPR-Cas13

New Broad Institute ‘REPAIR’ system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome. The Broad Institute and MIT scientists who first harnessed CRISPR for mammalian genome editing have engineered a new molecular system …

crisprGene defect fixed in 8 out of 20 cloned embryos, heralds future of gene fixes and enhancement

A team in China has taken a new approach to fixing disease genes in human embryos. The researchers created cloned embryos with a genetic mutation for a potentially fatal blood disorder, and then precisely corrected the DNA to show how …