Finding the 3D Structure of DNA for Stem Cell and Cancer Research Progress

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds. The genome is the complete set of genetic instructions, DNA or RNA, enabling an organism to function. …

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The Far Future and Using Atomic Precision for the Next Level of Technology

Adam Brown (Stanford) and Robin Hanson (George Mason University) talk about some interesting intellectual concepts for the distant futures in the conference video below. Christine Peterson, Foresight Institute, talks about getting to the next level. She highlighted the need for molecular nanotechnology. Leveraging various forms of atomically precise capabilities are starting to reach interesting new …

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DNA, RNA Reading Just Got Thousands of Times Faster

DNA, RNA and protein reading just got thousands of times faster with the commercial release of Roswell Biotechnologies molecular electronics chip. The first molecular electronics chip has been developed. This is realizing a 50-year-old goal molecular nanotechnology to integrate single molecules into circuits to achieve the ultimate scaling limits of Moore’s Law. It was developed …

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A World With Cheap Aging Damage Reversal

What would a world with cheap aging damage reversal look like? This could happen with biotech or gene therapy injections that repair aging damage. Oisin Biotechnologies has been developing a highly precise, patent-pending, DNA-targeted intervention to clear these cells. There is also work by Rejuvenate Bio to create injectable combination gene therapy that could reverse …

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New Gene Editing Tool for Millions of Edits

There is a new gene-editing tool called Retron Library Recombineering (RLR) that makes this task easier that has been developed by George Church and his team. RLR generates up to millions of mutations simultaneously, and “barcodes” mutant cells so that the entire pool can be screened at once, enabling massive amounts of data to be …

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Self-healing Fabric

A DNA construct is an artificially constructed segment of nucleic acid. It can be isolated or integrated in another DNA molecule. A recombinant DNA construct is produced by laboratory methods. Polynucleotide constructs with at least one disruption or tearing responsive promoter and at least one sequence encoding a fiber-forming protein. A cell with such constructs …

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Genome Editing Anti-cancer System

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The system, called CRISPR-LNPs, carries …

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Meta DNA Revolutionizes DNA Nanotechnology By Scaling Up Size By 1000 to 1 Million Times

The new meta-DNA self-assembly concept may totally transform the microscopic world of structural DNA nanotechnology. Decades ago a huge milestone in DNA technology was the invention of DNA origami, where a long single-stranded DNA is folded into designated shapes with the help of hundreds of short DNA staple strands. DNA nanotechnology had challenges assembling larger …

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