Motorized molecules drill into cancer cells

Motorized molecules driven by light have been used to drill holes in the membranes of individual cells, including cancerous ones. The technique shows promise for either bringing therapeutic agents into the cells or directly inducing the cells to die. Dr Robert Pal at Durham University worked with researchers at Rice and North Carolina State universities …

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FDA approves $475K Leukemia gene therapy treatment with 83% success rate

The Food and Drug Administration on Wednesday announced what the agency calls a “historic action” — the first approval of a cell-based gene therapy in the United States. The FDA approved Kymriah, which scientists refer to as a “living drug” because it involves using genetically modified immune cells from patients to attack their cancer. The …

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China’s Navy in the 2020s will have a lot of modern subs, carriers and sea bases

China’s naval modernization effort encompasses a wide array of platform and weapon acquisition programs, including anti-ship ballistic missiles (ASBMs), anti-ship cruise missiles (ASCMs), submarines, surface ships, aircraft, and supporting C4ISR (command and control, communications, computers, intelligence, surveillance, and reconnaissance) systems. China’s naval modernization effort also includes improvements in maintenance and logistics, doctrine, personnel quality, education …

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Nerve Cells restored in Monkeys with Parkinsons like disease

Parkinson’s disease causes the progressive loss of nerve cells that release dopamine, a chemical that helps control body movement. The researchers triggered a similar loss of cells in macaque monkeys, then used human stem cells to replace them. They hope to have human clinical trials in 2018. The animals showed significant improvement in their symptoms …

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Single-nucleus RNA sequencing, droplet by droplet

DroNc-Seq — a technology that merges single-nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues. Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This system enabled researchers to study the gene expression profiles of difficult-to-isolate cell types as well as cells from archived tissues. …

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Offshore vaccine tests to shortcut FDA delays

Peter Thiel is backing the offshore testing of an experimental herpes vaccine. Thiel invested $7 million in the ongoing vaccine research, according to the U.S. company behind it. Southern Illinois University also trumpeted the research and the study’s lead researcher, even though he did not rely on traditional U.S. safety oversight in the first trial, …

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Metformin could be the first FDA approved antiaging drug

For the last two decades, researchers started comparing the health of diabetics on metformin to those taking other diabetes drugs. Metformin-takers tended to be healthier in all sorts of ways. They lived longer and had fewer cardiovascular events, and in at least some studies they were less likely to suffer from dementia and Alzheimer’s. Most …

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Surplus volunteer computer power for Microbiome Immunity Project

The Microbiome Immunity Project is a new, IBM-facilitated citizen science project by scientists from the Broad Institute of MIT and Harvard, Massachusetts General Hospital, University of California San Diego, and the Simons Foundation’s Flatiron Institute. It will use the surplus processing power on volunteers’ computers to conduct millions of virtual experiments on behalf of the …

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Antennas 100 times smaller than today could enable tiny brain implants and other breakthroughs

Engineers have figured out how to make antennas for wireless communication 100 times smaller than their current size, an advance that could lead to tiny brain implants, micro–medical devices, or phones you can wear on your finger. The brain implants in particular are “like science fiction,” says study author Nian Sun, an electrical engineer and …

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