Graphene-Based Neural Probes Probe Brain Activity in High Resolution

Measuring brain activity with precision is essential to developing further understanding of diseases such as epilepsy and disorders that affect brain function and motor control. Neural probes with high spatial resolution are needed for both recording and stimulating specific functional areas of the brain. Now, researchers from the Graphene Flagship have developed a new device …

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the drug everolimus boosts flu vaccine response by 25% in people over 65 and rejuvenates the immune system

Novartis found that giving low doses of a drug called everolimus to people over 65 increased their response to flu vaccines. It did, by about 20 percent. Yet behind the test was a bigger question about whether any drug can slow or reverse the symptoms of old age. Novartis’s study on everolimus, which looked at …

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Silicon Valley’s pursuit of extreme life extension

The New Yorker magazine looks at silicon valley’s anti aging activities. It covers the usual work and ideas of Aubrey de Grey (SENS repairing 7 kinds of aging related damage) and Ray Kurzweil (Singularity and uploading). Unity Biotechnology Unity Biotechnology targets senescent cells—cells that, as they age, start producing a colorless, odorless, noxious goo called …

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Around ten million lives per year could be saved from Sepsis using $60 treatment of intravenous Vitamin C, Vitamin B and hydrocortisone

Patients in Norfolk with severe Sepsis were treated with intravenous vitamin C, hydrocortisone and thiamine. In 47 patients with sepsis treated in Norfolk General’s ICU, four died in 2016, an 8 percent mortality rate. Of those four, none died of sepsis but rather the conditions that led to sepsis in the first place. The previous …

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Critical step in cellular repair of damaged DNA identified which could be big for reversing aging and human trials will start within six months

UNSW researchers have identified a critical step in the molecular process that allows cells to repair damaged DNA – and it could mean big things for the future of anti-ageing drugs, childhood cancer survivors and even astronauts. It could lead to a revolutionary drug that actually reverses ageing, improves DNA repair and could even help …

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Gene sequencing for rapid diagnosis of tuberculosis and prompt initiation of correct life saving treatment

British scientists have made a world-first breakthrough in the diagnosis of tuberculosis using gene sequencing. The diagnosis can be made in days instead of months. This will enable the prompt treatment with the correct drugs. Researchers in Oxford and Birmingham say they can isolate different strains of the disease using a process called genome sequencing. …

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Two separate breakthroughs will combine for unlimited youthful blood for antiaging and immune system boosting transfusions

Two separate breakthroughs will combine for unlimited youthful blood for antiaging and immune system boosting transfusions 1. Immortalized cell lines can enable factory mass produced red blood cells 2. An activated protein can make blood youthful which boosts immune systems This could be the first cells and tissue that could be immortalized and used for …

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CRISPR/Cas9 Reveals Cancer’s Synthetic Lethal Vulnerabilities

The CRISPR/Cas9 gene-editing system has been used to identify more than 120 synthetic-lethal gene interactions in cancer cells. These interactions could guide drug developers to new combination therapies that could selectively kill cancer cells and spare healthy cells. Synthetic-lethal gene interactions may occur when certain pairs of mutated genes are present. When there is a …

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CRISPR gene therapy is enhancing t-cell immnotherapy treatment of cancer and treatments in people could be available within 2 to 3 years

Marcela V. Maus, M.D., Ph.D., of Harvard Medical School identified three important improvements that CRISPR gene editing could potentially bring to T-cell-based therapies. 1. being more-effective tumor responses. 2. the targeted nature of CRISPR-mediated CAR integration into the genome might “prove safer than random integration, which carries the potential risk of generating a harmful mutation,” …

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Vaccine that does not need refrigeration could save 500,000 lives each year from fatal diarrhoea

Positive outcome of trials in Niger fuels hope that vaccine can protect children in sub-Saharan Africa and beyond from infection that causes often fatal diarrhoea. A vaccine capable of enduring scorching temperatures for months at a time could strike a decisive blow in the fight against rotavirus, preventing nearly half a million children around the …

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Some aging reversal in appearance, liver, muscle and other functions with cell penetrating peptides in very old mice

Researchers have rejuvenated old mice to restore their stamina, coat of fur and even some organ function. The team at Erasmus University Medical Center, in the Netherlands, are planning human trials for what they hope is a treatment for old age. A UK scientist said the findings were “impossible to dismiss”, but that unanswered questions …

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