A transformative artificial intelligence (AI) tool called AlphaFold, which has been developed by Google’s sister company DeepMind in London, has predicted the structure of nearly the entire human proteome (the full complement of proteins expressed by an organism). In addition, the tool has predicted almost complete proteomes for various other organisms, ranging from mice and …
A DNA construct is an artificially constructed segment of nucleic acid. It can be isolated or integrated in another DNA molecule. A recombinant DNA construct is produced by laboratory methods. Polynucleotide constructs with at least one disruption or tearing responsive promoter and at least one sequence encoding a fiber-forming protein. A cell with such constructs …
Deep Mind has been able to make significant progress toward solving the protein folding problem. Protein folding is not solved yet. Here I will describe : * the complexity the protein folding problem. 10^300 folding possibilities for the the average protein based upon certain assumptions * I will compare the other large problems to protein …
Researchers at Kyushu University have developed highly efficient amino acid synthesis from biomass-derivable acids and water using electric energy. Amino acids are the basic building blocks of proteins and are also involved in various functional materials such as feed additives, flavor enhancers, and pharmaceuticals. Above – A demonstration flow reactor constructed by researchers at Kyushu …
ProteinQure uses quantum computing, molecular simulations and reinforcement learning to engineer new drugs. They combine state-of-the-art structure-based algorithms, including molecular dynamics simulations and machine learning. Their design platform explores vast regions of sequence space and predict functional properties of therapeutics to rapidly deliver new insights to their partners in pharmaceutical R&D. ProteinQure can obtain structures …
Nanoblades Are Another Delivery Option for Gene Editing into Live Organisms
Proteins are major building blocks of life. The protein content of a cell and an organism provides key information for the understanding of biological processes and disease. Despite the importance of protein analysis, only a handful of techniques are available to determine protein sequences, and these methods face limitations, for example, requiring a sizable amount …
Unit 4 of the Yangjiang nuclear power plant in China’s Guangdong province has completed commissioning tests and now meets the conditions for entering commercial operation, China General Nuclear (CGN) announced on March 15, 2017. The loading of fuel assemblies into the core of the 1080 MWe CPR-1000 pressurised water reactor was completed on 21 November …
Robert Zubrin makes the case that innovation and innovative people and scientific progress increases resources. Hitler and Malthus made the case that there is only so much to go around and you must fight and kill for it. However, there was 1 billion people at the time of Malthus and they had the equivalent in …
Gallium nitride (GaN) has emerged as one of the most important and widely used semiconducting materials. Its optoelectronic and mechanical properties make it ideal for a variety of applications, including light-emitting diodes (LEDs), high-temperature transistors, sensors and biocompatible electronic implants in humans. Four Lehigh engineers have reported a previously unknown property for GaN: Its wear …
A star known by the unassuming name of KIC 8462852 in the constellation Cygnus has been raising eyebrows both in and outside of the scientific community for the past year. In 2015 a team of astronomers announced that the star underwent a series of very brief, non-periodic dimming events while it was being monitored by …
