HIV drugs turned what was a death sentence within about 5 years into a chronic condition where treated people have almost the same lifespan as those who are not infected. Currently, HIV drugs cost $75 in Africa and $39,000 in the U.S. The distribution of treatment and costs could represent what might happen with the …
Jim Mellon is a billionaire investor in antiaging companies. Jim has made several investments in antiaging companies and as one of the leading investors in the field gets pitched almost all of the antiaging companies. Jim thus has a unique perspective on what the latest developments are with anti-aging technology. Jim predicts that average life …
Bill Faloon is the co-founder of the Life Extension nutritional supplement company and founder of the Church of Perpetual Life in Hollywood, Florida. Bill was at the Raadfest 2018, which is an antiaging conference which had an attendance of about 1000 people. Bill is like others who attend Raadfest who want to take any antiaging …
Salk Institute researchers have used CRISPR/Cas9 therapy to suppress aging, enhance health and extend life span in mice. Above – This image shows two mice of the same age with progeria. The larger and healthier mouse on the left received the gene therapy, while the mouse on the right did not. Credit: Salk Institute They …
The entire genome of the white shark has now been decoded in detail. The white shark genome was also compared to gthe genomes of other vertebrates including the giant whale shark and humans. The white shark has a genome that is one and half time larger than the human genome. Very large-bodied animals do not …
A new antigaging group has been formed to accelerate the development of scientific documented interventions that will promote longer, healthier, more productive and more rewarding lives for all members of humanity. The Academy for Health and Lifespan Research will host forums to share research findings. They will lobby governments in the United States, Europe, and …
Newcastle University researchers are exploring the effects of removing senescent cells that form as a result of a heart attack. Heart cells, cardiomyocytes, rarely divide it was not known how these cells could become senescent. Senescent cells are also called zombie cells. Zombie cells do not function correctly and can cause other cells around them …
Goldman Sachs analysts asked “Is curing patients a sustainable business model?” analysts ask in an April 10 report entitled “The Genome Revolution.” Goldman was addressing the question of gene therapies that provide complete cures with one treatment. “The potential to deliver ‘one shot cures’ is one of the most attractive aspects of gene therapy, genetically-engineered …
In 2001, Aubrey de Grey and colleagues proposed ablation of senescent cells (ApoptoSENS) as the “damage-repair” strategy of choice for zombie cells. The idea was barely mentioned in the scientific literature. It was largely ignored until 2011 when a powerful proof-of-concept study showed that killing these “zombie cells” using a genetically-engineered “suicide switch” substantially rejuvenated …
Dr. James Peyer of ApolloVC discussed tactical paths to bring longevity promoting therapeutics to market as quickly as possible. The cost of developing a drug is $2.6 billion. Pharma companies need to have each successful drug approved has to pay for ten failed drugs. Each drug from discovery through clinical trials averages out to a …
Unity Biotechnology is a biotech leader in developing treatments to eliminating accumulated senescent cells, which are a fundamental mechanism of aging and a driver of many common age-associated diseases. Senescent cells normally destroy themselves via a programmed process called apoptosis, and they are also removed by the immune system; however, the immune system weakens with …