Reading and Writing DNA has improved 2 to 10 times faster than Moore’s Law over the last 35 years. There has been over 10 million times improvement. Molecular and cell multiplexing enable atomically precise reactions at 1 trillion reactions per droplet. George Church gave a talk about reading and writing whole genomes. George Church giving …
Bio-inspired Quorum Sensing in robots fabricated from DNA origami can communicate by transmitting and receiving diffusing chemical signals. The mechanism has features such as programmable response thresholds and quorum quenching, and is capable of being triggered by proximity of a specific target cell. Nanoscale robots with swarm intelligence could carry out tasks that have been …
DNA is a reliable biomolecule with which to build molecular computation systems. DNA logic circuits (diffusion-based) have shown good performance regarding scalability and correctness of computation. However, previous architectures of DNA logic circuits have two limitations. 1. The speed of computation is slow, often requiring hours to compute a simple function. 2. The circuits are …
Researchers at Los Alamos National Laboratory have created the largest simulation to date of an entire gene of DNA, a feat that required one billion atoms to model and will help researchers to better understand and develop cures for diseases like cancer. “It is important to understand DNA at this level of detail because we …
George Church describes going beyond cutting DNA to precise editing. 1. Phage Integrases (Protein and DNA) 2. TAL Deaminases (custom Protein) 3. Chemical Targeting (custom polymer) 4. lambda (λ)-red recombinase (Custom DNA) Beyond editing to writing large genomes DNA-based target recognition For DNA-based target recognition systems, the two major approaches, multiplex automated genome engineering (MAGE) …
George Church revealed progress on aging reversal using gene therapies. They have delivered 45 gene therapies to provide aging reversal. They find the combined treatment is effective against obesity, diabetes, osteoarthritis, cardiac damage and kidney disease. At 32:00-33:30 minutes George Church specifically describes delivering 45 age reversing gene therapies to treat multiple age related diseases. …
The goal of woolly mammoth project is to solve the permafrost climate issue. The top area of the world is covered in permafrost. The Siberian and Canadian tundra is this mass of permafrost and that permafrost is a ticking time bomb it contains within it more carbon, carbon dioxide and methane than if we burned …
George Church is developing better and better organs using pigs. They are working to slow or reverse the aging in the organs to be used for transplant. [about 8:40 in the video] He says the organ longvity has also been done successfully with entire mice. They have mice that live twice as long. He says …
Arizona State University (ASU) scientists, in collaboration with researchers from the National Center for Nanoscience and Technology (NCNST), of the Chinese Academy of Sciences, have successfully programmed nanorobots to shrink tumors by cutting off their blood supply. Above – Nanorobots can be programmed to transport molecular payloads and cause on-site tumor blood supply blockages, which …
Arizona State University Professor Hao Yan and his colleagues describe an innovative DNA walker, capable of rapidly traversing a prepared track. Rather than slow, tentative steps across a surface, the new DNA acrobat cartwheels head over heels, covering ground 10 to 100 times faster than previous devices. Above -Hao Yan, director of the Biodesign Center …
n a major advancement in nanomedicine, Arizona State University scientists, in collaboration with researchers from the National Center for Nanoscience and Technology (NCNST) of the Chinese Academy of Sciences, have successfully programmed nanorobots to shrink tumors by cutting off their blood supply. “We have developed the first fully autonomous, DNA robotic system for a very …